Equipment for dynamically simulating and testing biodegradability of medical magnesium alloy in vitro

Abstract

A medical magnesium alloy biodegradability in vitro dynamic simulation test device includes a thermostatic bath (1), a liquid storage tank (2), a circulation pump (3), a flow meter (4), a test cabin (5), an upper sample loader (6), a liquid absorbing tube (7) and a backflow tube (8). The liquid absorbing tube (7) and the backflow tube (8) are arranged in the liquid storage tank (2), respectively. The liquid storage tank (2) is arranged in the thermostatic bath (1). The flow meter (4) and the test cabin (5) are vertically arranged, respectively. The upper sample loader (6) pierces the top cover (20) and is hung in the test cabin (5). The test device has water tubes respectively arranged between inlets of the liquid absorbing tube (7) and the circulation pump (3), between an outlet of the circulation pump (3) and an inlet of the flow meter (4), and between an outlet of the flow meter (4) and the cabin inlet tube (9) of the test cabin (5). The water tubes are further arranged between the cabin outlet tube (10) of the test cabin (5) and the backflow tube (8) for connection to compose a liquid medium circulation path. The device provides a compact structure, convenient use and strong commonality, and provides fast and accurately test and evaluation of the influence of the flow speed, the component, the temperature and the PH value of a medium on the medium corrodibility and the material degradation.

Description

technical field [0001] The invention belongs to the field of material performance testing technology and equipment, and relates to a device for dynamic simulation test and evaluation of material corrosion degradation performance in a fluid medium, especially suitable for biomedical materials / apparatus such as medical magnesium alloy and its medical equipment biodegradation In vitro dynamic simulation testing of performance. Background technique [0002] For materials serving in a liquid environment, such as medical devices implanted in the human body, ships in seawater, etc., the relative motion between them and the medium has a very important impact on their corrosion degradation behavior. Studies have shown that this relative movement can not only change the corrosion degradation rate of the material / device, but also change its corrosion degradation type and its mechanism. Therefore, simulating the actual service conditions, especially the relative movement between the en...

AI Technical Summary

Problems solved by technology

Although this method is simple and easy to implement, it has the following main disadvantages: 1) It ignores the important influence of the relative motion of the material / medium on the corrosion degradation behavior of the material except convection

The biomedical application of magnesium alloy is just around the corner, especially when it is used as a coronary stent, it will inevitably be sheared by flowing body fluids such as blood, tissue fluid, etc.; It is difficult to accurately predict the in vivo biodegradability of materials / devices, which greatly reduces its clinical reference value, thus losing the due significance of in vitro research

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