Chinese medicinal detoxifying myo-regeneration paste for treating diabetic foot ulcer and preparation method thereof

Abstract

The invention provides Chinese medicinal detoxifying myo-regeneration paste for treating diabetic foot ulcer, which belongs to the fields of traditional Chinese medical science and traditional Chinese medicines. The paste is prepared from the following raw materials in percentage by weight: 6 to 11 percent of rhubarb, 6 to 11 percent of golden thread, 6 to 11 percent of amur corktree bark, 14 to 19 percent of plaster, 12 to 17 percent of sinkiang arnebia root, 14 to 20 percent of Chinese angelica, 7 to 11 percent of angelica dahurica, 2 to 5 percent of calomel, 7 to 11 percent of dragon's blood and 23 to 30 percent of bee wax. Animal experiments and clinical researches prove that the Chinese medicinal detoxifying myo-regeneration paste provided by the invention has the effects of activating blood, dissolving stasis, removing putrefaction, regenerating myo, clearing away heat and toxic material and the like, has the advantages of keeping the surface of a wound wet, increasing the content of cell factors, namely, a vascular endothelial growth factor (VEGF) and a platelet-derived growth factor (PDGF) and promoting relevant gene expressions of muscles and blood vessels, along with definite curative effect, simple and convenient operation, economy, safety and no toxic or side effect and special significance in treating diabetic foot ulcer.

Description

Technical field: [0001] The invention belongs to the field of traditional Chinese medicine, and relates to a traditional Chinese medicine detoxifying ointment for clinically treating diabetic foot ulcers and a production process thereof. Background technique: [0002] Diabetic foot ulcer is recognized as the first of the four obstinate complications in the world. It develops slowly, has a long course of disease, causes great pain, complex treatment, low curative effect, high cost, and high amputation rate. Every day, 2,880 people in the world amputate due to diabetic foot ulceration. The amputation rate of diabetic feet in foreign countries is as high as 50%, while the domestic amputation rate is 20%-30%. Diabetic patients have a significantly higher risk of lower limb gangrene than non-diabetic patients (about 15 times) ), the mortality rate of diabetic patients with foot ulcers is about twice that of diabetic patients without foot ulcers. The treatment cost of diabetic fo...

AI Technical Summary

Problems solved by technology

[0006] (4) Surgical operations and interventional therapy: Arterial stents, balloon dilatation, arterial plaque ablation, arterial plaque atherectomy, artificial vascular bypass, etc. require sophisticated and expensive equipment, heavy trauma, high risk, high cost, and many complications , high mortality, poor patient compliance

[0007] (5) Stem cell therapy: The required equipment is sophisticated and expensive, and due to ethical restrictions, most hospitals cannot carry out it, and the long-term efficacy remains to be seen

[0013] (11) Traditional Chinese medicine ointment for external use: Although there are many treatment methods for diabetic foot, most of the medical equipment is expensive, the treatment cost is high, the curative effect is inaccurate, the risk is high, and there are many complications. Treatments with fewer comorbidities have long puzzled clinicians

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