Traditional Chinese medicine preparation of new Zhongsheng pill and preparation method thereof
A technology for traditional Chinese medicine preparations and Zhongsheng Pills, which is applied in the directions of pill delivery, pharmaceutical formulations, and non-active ingredients medical preparations, etc. The problems of different sizes, etc., can shorten the production cycle, lengthen the dissolution time limit, and reduce the drying process.
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Embodiment 1
[0126] Example 1 (Preparation of Xinzhongsheng Pills):
[0127] 160g of dry ointment powder of Zhongsheng pills, 30g of bilinanstar powder, 20g of artificial bezoar, 50g of hydroxypropyl cellulose, 37.5g of microcrystalline cellulose, 38.5g of lactose, 4g of silicon dioxide, and 5g of magnesium stearate to make 1000 pills.
[0128] Take 1 / 2 bilinanstar powder and lactose through a 0.8mm sieve (50Hz) with a granulator, and then feed them into the mixer together with the remaining bilinanstar powder, artificial bezoar, hydroxypropyl cellulose and microcrystalline cellulose , Pre-mixed for 20 minutes and then release the material. [U6] Take the dry ointment powder of Zhongsheng Pills, the premix of bilinanstar powder and lactose, artificial bezoar, hydroxypropyl cellulose, microcrystalline cellulose, silicon dioxide, magnesium stearate After passing through a 2.5mm sieve (45Hz) with a granulator, the materials are fed into the mixer together and mixed for 30 minutes. Pills are made b...
Embodiment 2
[0129] Example 2 (Preparation of Xinzhongsheng Pills):
[0130] Zhongsheng Pills dry powder 200g, bilinanstar 30g, artificial bezoar 20g, hydroxypropyl cellulose 40g, microcrystalline cellulose 25g, lactose 25g, silicon dioxide 5g, magnesium stearate 5g, made into 1000 pills.
[0131] Take 1 / 2 bilinanstar powder and lactose through a 0.8mm sieve (50Hz) with a granulator, and then feed them into the mixer together with the remaining bilinanstar powder, artificial bezoar, hydroxypropyl cellulose and microcrystalline cellulose , Pre-mixed for 20 minutes, then release the material, take the dry ointment powder of Zhongsheng pill, the premix of bilinanstar powder and lactose, artificial bezoar, hydroxypropyl cellulose, microcrystalline cellulose, silicon dioxide and magnesium stearate The granulator passes through a 2.5mm sieve (45Hz) and is fed into the mixer together for a total of 30 minutes of mixing. Pills are made by high-speed pill pressing, the size of the spherical die is 7.9m...
Embodiment 3
[0132] Example 3 (Preparation of Xinzhongsheng Pill):
[0133] Zhongsheng Pill dry cream powder 160g, bilinanstar powder 30g, artificial bezoar 20g, hydroxypropyl cellulose 14.5g, microcrystalline cellulose 18.5g, lactose 18.5g, magnesium stearate 1.25g, silicon dioxide 2.5g, made into 1000 pills .
[0134] Take 1 / 2 bilinanstar powder and lactose through a 0.8mm sieve (50Hz) with a granulator, and then feed them into the mixer together with the remaining bilinanstar powder, artificial bezoar, hydroxypropyl cellulose and microcrystalline cellulose , Pre-mixed for 20 minutes, then release the material, take the dry ointment powder of Zhongsheng pill, the premix of bilinanstar powder and lactose, artificial bezoar, hydroxypropyl cellulose, microcrystalline cellulose, silicon dioxide and magnesium stearate The granulator passes through a 2.5mm sieve (45Hz) and then is fed into the mixer together for a total of 30 minutes of mixing. The pellets are made by high-speed pill pressing, th...
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