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Glabrous sarcandra herb formula particle and preparation method thereof

A technology for formula granules and Zangjiefeng, which is applied in pharmaceutical formulations, medical preparations containing active ingredients, antitumor drugs, etc., can solve problems such as the preparation process of no Zangjiefeng formula granules, and achieve stable and controllable product quality. , The effect of easy to deploy formula and simple preparation process

Inactive Publication Date: 2010-12-01
江西省药物研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there is no report about Zhongjiefeng Formula Granules and its preparation process

Method used

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  • Glabrous sarcandra herb formula particle and preparation method thereof
  • Glabrous sarcandra herb formula particle and preparation method thereof

Examples

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Effect test

example 1

[0033] Take 500g of sargassum, crush it, add 4000g of water, reflux at 99°C for 1.5 hours, reflux for 3 times, combine and extract the medicinal liquid, filter, and concentrate the filtrate to a thick paste with a relative density of 1.20-1.30 under normal pressure , continue to dry, grind into dry powder, get 70g of sargassum extract, add 80g of soluble starch, make soft material with 45ml of 60% ethanol, make granules through No. 14 sieve, dry under normal pressure at 60°C, use No. 1 Sieve and No. 5 sieve double sieve to get, make 150g of sarcophagus formula granules, every 3 grams is equivalent to 10 grams of sarcophagus medicinal material, pack into bags, and each bag is filled with 0.9g, 1.5g, 3g.

example 2

[0035] Take 500g of sargassum, crush it, add 5000g of water, reflux at 100°C for 2 hours, reflux for 3 times, combine and extract the medicinal liquid, filter, and concentrate the filtrate to a thick paste with a relative density of 1.20-1.30 under reduced pressure , continue to dry, grind into dry powder, get 72g of Sargassum extract, add 78g of dextrin, make soft material with 50ml of 80% ethanol, pass through No. 14 sieve to make granules, dry under normal pressure at 60°C, Sieve and No. 5 sieve double sieve to get, make 150g of sarcophagus formula granules, every 3 grams is equivalent to 10 grams of sarcophagus medicinal material, pack into bags, and each bag is filled with 0.9g, 1.5g, 3g.

example 3

[0037]Take 500g of sargassum, pulverize it, add 6000g of water, reflux at 100°C for 2.5 hours, reflux and extract twice, combine and extract the medicinal liquid, filter, and concentrate the filtrate to a thick paste with a relative density of 1.20-1.30 under normal pressure , continue to dry, and grind into dry powder to obtain 73g of sargassum extract, add 80g of starch, 67g of lactose, make a soft material with 45ml of 90% ethanol, make granules through a No. 14 sieve, dry under normal pressure at 60°C, and use No. 1 sieve and No. 5 sieve were double-sieved to obtain 200 g of sarcophagus formula granules, each 2 g is equivalent to 5 g of sarcophagus medicinal material, and packed into bags, each bag containing 1 g, 2 g, and 4 g.

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Abstract

The invention relates to a glabrous sarcandra herb formula particle and a preparation method thereof, belonging to the traditional Chinese medicine formula particle preparation technology. Glabrous sarcandra herb is subject to water extraction and concentration, appropriate auxiliary material is added, and formula particle is prepared, content of active components isofraxidin and total flavones in the glabrous sarcandra herb is high, quality is stable and controllable, the specification of the prepared formula particle is that every 1-5g glabrous sarcandra herb formula particle is equivalent to 3-15g fresh glabrous sarcandra medicinal material. The invention can meet the requirements on clinic syndrome differentiation and treatment and add-minus according to the disease and is beneficial for doctors to make a prescription flexibly. The invention changes the traditional glabrous sarcandra medicinal material into particles, the stability of the invention is improved, the invention is easy to store and carry, formula is flexible, dosage is less, and use is convenient.

Description

technical field [0001] The invention relates to a sargassum formula granule and a preparation method thereof, belonging to the preparation technology of traditional Chinese medicine formula granules. Background technique [0002] Traditional Chinese medicine formula granules are also called traditional Chinese medicine granule decoction pieces, decoction-free decoction pieces, and single-flavor Chinese medicine concentrated granules. It is a new dosage form of traditional Chinese medicine decoction pieces made by scientifically processing single Chinese medicine and extracting active ingredients in Chinese herbal medicines. It is one of the development directions of Chinese medicine decoction pieces and one of the important research contents of the modernization of Chinese medicine. Clinical application and pharmacological experiments have shown that single Chinese medicine formula granules have basically the same curative effect and pharmacological effects as traditional wa...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61K9/16A61P1/00A61P11/00A61P31/12A61P35/00
Inventor 朱才庆周斌曾宪仪李燕吴迪李忠贵余华罗强云夏平范其坤
Owner 江西省药物研究所
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