Novel membrane spraying preparation for skin trauma and preparation method

Abstract

The invention discloses a medicinal membrane spraying preparation for skin trauma and a preparation method thereof, and relates to the field of medicinal preparations. The medicinal membrane spraying preparation consists of a blank membrane spraying preparation and medicinal components dissolved in the blank membrane spraying preparation and having skin trauma treating effective concentration. The medicinal membrane spraying preparation is characterized in that the blank membrane spraying preparation comprises the following components in percentage by mass: 0.3 to 8 percent of polyvinyl alcohol PVA0588, 0.5 to 5 percent of polyvinyl alcohol PVA 1788 and / or 1 to 10 percent of polyvinyl butyral (PVB), 0 to 5 percent of humectant, 0 to 2 percent of fragrance, 0 to 10 percent of viscosity regulator and the balance of solvent; the solvent is 60 to 100 percent ethanol, ethyl acetate, acetone and / or propylene glycol; and the viscosity regulator is polyoxyethylene hydrogenated castor oil RH40or polyoxyethylene castor oil EL35. When the membrane spraying preparation is sprayed on a skin wound, a membrane is formed within one minute, the membrane maintaining time reaches 5 hours, and the preparation can quickly stop blood and clot blood; and the preparation can save the steps of dressing, replacing gauze, sterilizing and the like with injury to the skin, is favorable for wound healing and does not leave scars.

Description

technical field [0001] The invention relates to the field of medical preparations, in particular to a novel spray film preparation and a preparation method for skin trauma including burns, scalds, abrasions, superficial open wounds and superficial open injuries. Background technique [0002] Skin is an important organ of the human body, composed of epidermis and dermis, and has important physical, chemical and biological barrier functions. It covers the surface of the whole body and has the most contact with the external environment. In daily work and life, people often suffer from skin trauma such as abrasions, cuts, scalds, and burns. Various damages caused by skin trauma, such as: increased metabolism, decreased body temperature, excessive loss of water and protein, and disorders of the endocrine and immune systems. Although most skin traumas are superficial injuries, improper treatment will lead to delayed healing, slow wound healing, and affect work and study. If not ...

AI Technical Summary

Problems solved by technology

The above spray film preparations can partially overcome the current problem of treating skin trauma to a certain extent, but these spray film preparations, because most of the film-forming auxiliary materials of spray film preparations are selected from Tween 80, glycerin, ethanol, polyvinylpyrrolidone, PVA124, etc. , so most of the film spraying is a hydration film, the film is thin, the film is brittle, the film formation time is relatively long (generally greater than 5min), the film maintenance time is short (less than 1h), and the wound infection is often caused by the long time in the film formation process , during use, because the film lasts for a short time, and is thin and brittle, it needs to be sprayed continuously to ensure that the wound is not infected. These shortcomings have brought a lot of inconvenience to the patient

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