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Pig blood composition and pig blood chewable tablet made therefrom

A technology of a composition and chewable tablets, which is applied in the field of pig blood chewable tablets, can solve the problems such as the quantity, preparation process and quality gap of Chinese medicine chewable tablets, and achieve the effect of low cost and promoting gastrointestinal motility

Inactive Publication Date: 2010-09-15
CHINA JILIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Compared with Western medicine, there is a big gap in the number of varieties, preparation process and quality of Chinese medicine chewable tablets

Method used

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  • Pig blood composition and pig blood chewable tablet made therefrom
  • Pig blood composition and pig blood chewable tablet made therefrom
  • Pig blood composition and pig blood chewable tablet made therefrom

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0081] 1 Materials and reagents

[0082] Pig blood that has been anticoagulated with sodium citrate (the amount of sodium citrate added is: add 3.8% sodium citrate aqueous solution of 1 / 9 of the mass of pig blood), black fungus produced in Northeast China; vitamin B 2 , vitamin C, microcrystalline cellulose, cyclamate, mannitol, pregelatinized starch, micronized silica gel, magnesium stearate are all pharmaceutical grade, hydroxypropyl β-cyclodextrin, chocolate flavor are food grade.

[0083] 2 experimental equipment

[0084] HMB-701 ultrafine pulverizer; HELDS / BF laser particle size analyzer; TEA-1 ultrasonic cleaning machine.

[0085] 3 Experimental methods and results

[0086] 3.1 Pig blood deodorization process

[0087]Take 500ml of pig blood in a 1000ml beaker, boil it in a boiling water bath for 10 minutes to form a coagulated mass, filter to remove the clear liquid, take 200g of the coagulated mass and grind it into a paste in a cooking machine; add 100g of hydroxypr...

Embodiment 2

[0115] Embodiment 2: pig blood deodorization process

[0116] 1. The deodorizing effect of hydroxypropyl β-cyclodextrin on pig blood

[0117] After the boiled coagulation of anticoagulant pig blood is made into a paste, add 1 / 8, 1 / 7, 1 / 6, 1 / 5, 1 / 4, 1 / 3, 1 / 2, 1 / 1 of hydroxypropyl β-cyclodextrin, in ultrasonic at a temperature of 50 ° C, with 30KHz ultrasonic treatment for 10min. Select 5 experienced sensory evaluators to sort the samples according to the specified characteristics according to the intensity of fishy smell, and score them on a 9-point scale, with 1 point for very dislike, 2 points for very dislike, and 3 points for dislike, 4 points for not liking it very much, 5 points for generally, 6 points for slightly liking, 7 points for liking, 8 points for liking very much, and 9 points for liking very much. The higher the score, the smaller the fishy and peculiar smell of the sample. The masking effect scores of the eight matching fishy smells were 5.2 points, 5.6 po...

Embodiment 3～8

[0126] Examples 3-8: Determination of the addition ratio of pig blood paste and black fungus superfine powder

[0127] Change the raw material formula of step 3.3 in embodiment 1, other raw material consumption and operation steps are the same as the steps in embodiment 1, and the proportion of pig blood paste ((PBP) and black fungus superfine powder (AASP) in the formula is larger, and the nutritional value The higher the higher, but also need to consider the forming effect of the chewable tablet and the needs of taste adjustment. Change the addition amount of pig blood paste and black fungus superfine powder, and keep the amount of other raw materials unchanged, carry out the tablet compression experiment, the results are shown in Table 3.

[0128] Table 3 Tablet test results of different proportions of black fungus superfine powder and seaweed powder

[0129]

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Abstract

The invention discloses a pig blood composition, mainly comprising the following components: 20-40 parts of pig blood, 10-20 parts of ultrafine black fungus powder, 0.5-2 parts of vitamin B2 and 3-12 parts of vitamin C. The pig blood is made into pig blood paste by embedding pig blood solution added with sodium citrate b for anticoagulation using hydroxypropyl beta-cyclodextrin, ; or boiling the pig blood solution added with sodium citrate for anticoagulation in a boiling water bath into a coagulated block and then filtering, taking the coagulated block and crushing into paste, then adding hydroxypropyl beta-cyclodextrin into the coagulated block (the mass of the added hydroxypropyl beta-cyclodextrin is 1 / 2 the mass of the coagulated block), and processing by ultrasonic of 20-40KHz for 10-20min. The ultrafine black fungus powder has a fineness higher than 300 meshes. The invention also discloses a pig blood chewable tablet made from the pig blood composition. The hydroxypropyl beta-cyclodextrin is taken as the wall material, and an embedding technique is combined with an ultrasonics technique so that an offensive smell of pig blood can be effectively hidden.

Description

(1) Technical field [0001] The invention relates to a pig blood composition which can be used to prevent iron-deficiency anemia caused by lack of nutrition and a pig blood chewable tablet made thereof. (2) Background technology [0002] Iron is an essential trace element in the human body. When iron is deficient in the body, iron deficiency or iron deficiency anemia will occur, especially for infants, children, pregnant, lactating, and menstrual women over 4 months old. serious. According to the standards of the World Health Organization, anemia accounts for about 30% of the world's population. Over the years, people have been researching and discussing its etiology and prevention measures, among which supplementation is an important and effective way to improve iron deficiency anemia. [0003] For a long time, FeSO has been the first choice clinically 4 preparations for the treatment of iron deficiency anemia, but FeSO 4 It has poor chemical stability, is easily oxidize...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/06A61K9/20A61P3/02A61P7/06A61K31/375A61K31/525A61K35/14A23L31/00
Inventor 张拥军何杰民李佳
Owner CHINA JILIANG UNIV
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