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Plant-based animal immune potentiator prepared by fermenting and developing radix astragali decoction dregs

An immune enhancer and technology for animals, which is applied in the field of plant-derived animal immune enhancer developed by the fermentation of astragalus dregs, to achieve the effect of simple production process, normal function and enhanced cellular immune function

Inactive Publication Date: 2012-07-04
JIANGSU NANNONG GAOKE ANIMAL PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The present invention is based on the fermentation activity of Cicadae spp., using astragalus dregs as a culture medium, and adopting solid fermentation technology to ferment a botanical animal immune enhancer with remarkable effects, which is the first case at home and abroad

Method used

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  • Plant-based animal immune potentiator prepared by fermenting and developing radix astragali decoction dregs
  • Plant-based animal immune potentiator prepared by fermenting and developing radix astragali decoction dregs
  • Plant-based animal immune potentiator prepared by fermenting and developing radix astragali decoction dregs

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] 1. Forty 14-day-old healthy Roman chicks were randomly divided into control group and test group, and they were all fed according to conventional methods. The chicks in the test group added the above-mentioned fermented product of medicinal residue to the normal diet, so that the mass fraction of the fermented product was 4%, and continued to add it for 30 days. Blood was collected from the wing vein at 10, 20, 30 and 40 days after the test, and ND-HI Antibody detection, ERFC test, determination of ANAE formation rate of peripheral blood T lymphocytes. At the end of the test, 10 chickens were randomly selected from each group, weighed, fasted for 24 hours with water supply, and killed by jugular vein bleeding. The bursa and spleen were collected respectively. The ratio of cyst to body and spleen to body was compared.

[0032] 2.1 Before the chicken Newcastle disease HI antibody detection test (14 days old) the chicken ND-HI antibody titer determination results of each g...

Embodiment 2

[0050] 1 Select 80 long × large binary weaned piglets (half male and female) aged (28±3) days, and the experimental pigs are ordinary experimental animals.

[0051] 1) Randomly divide into 2 treatment groups, each treatment group has 5 repetitions, each column is 1 repetition group, and each column has 8 piglets. The two treatment groups are: control group: fed basal diet; treatment group: basal diet + 200mg / kg fermented product. The experiment was carried out at Jiangning Moling Pig Breeding Co., Ltd., fully enclosed pig house, roof exhaust fan ventilation, slatted metal floor, raised on the net, and the house temperature was kept at 25-30 °C. Powder feeding, a small amount of multiple times, free access to food and water, conventional feeding and immunization, the test period is 30 days.

[0052] 2) On the 14th and 28th days of the experiment, 5 blood samples were collected from each treatment group before feeding in the morning, and the sterile anterior vena cava blood sam...

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Abstract

The invention provides a plant-based animal immune potentiator prepared by fermenting and developing radix astragali decoction dregs, which belongs to the field of biotechnology. The immune potentiator is prepared by mixing 55 mass percent of radix astragali decoction dregs serving as a raw material with 30 mass percent of corn flour, 10 mass percent of bran and 5 mass percent of carbamide to prepare a decoction dreg fungal solid culture medium, wherein the material to water volume ratio of a fermentation system is 1:2; adjusting the PH to 5.0, inoculating Cordycepscicadae serving as a fermentation strain, wherein the temperature is kept between 25 and 30 DEG C in a fermentation process and the fermentation lasts for 240 hours. The fermented product can be directly or indirectly added into a feed for poultry or pigs to be used as the animal immune potentiator. The immune potentiator has the advantages that: raw materials are widely available; the production cost is low; the immune enhancement effect is desirable; environmental pollution is avoided in a production process; waste materials are converted into things of value; the fermented product is safe to people and animals; and the effect is remarkable. The immune potentiator is a non-polluted immune potentiator.

Description

technical field [0001] The invention relates to a botanical animal immune enhancer developed by fermentation of astragalus dregs, belonging to the technical field of feed, and is specially used for the plant-derived animal immune enhancer developed by fermentation of astragalus dregs. Background technique [0002] In recent years, with the rapid development of my country's traditional Chinese medicine pharmaceutical industry, the extraction and processing capacity of traditional Chinese medicine has been continuously improved, the types of products have become increasingly diverse, and the discharge of medicinal residues has increased year by year. According to statistics, Chinese medicine pharmaceutical companies will produce tens of millions of tons of traditional Chinese medicine dregs every year, and more than 90% of the manufacturers use the dregs as waste, which to a certain extent has caused a huge waste of plant resources. If it is not treated in time, it will cause ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23K1/16A61K36/481A61P37/04
Inventor 曹映海张笑意
Owner JIANGSU NANNONG GAOKE ANIMAL PHARMA CO LTD
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