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Composition with functions of clearing heat and detoxicating and preparation method thereof

A heat-clearing and detoxifying and composition technology, which is applied in the direction of medical preparations containing active ingredients, drug combinations, active ingredients of hydroxyl compounds, etc., can solve problems such as shock, insignificant systemic effects, and accelerated catabolism

Active Publication Date: 2010-06-09
江苏天济药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

(2) Thermal burns with a small systemic reaction area and relatively superficial surface, except for pain stimulation, have no obvious impact on the whole body
However, if hypovolemia exceeds the body's ability to compensate, shock can result
2. Insufficient energy and nitrogen negative balance After injury, the body's energy consumption increases, catabolism accelerates, and nitrogen negative balance occurs
4. Decreased immune function Post-injury hypoproteinemia, increased oxygen free radicals, release of certain factors (such as PGI2, IL-6, TNF, etc.), can reduce immunity; plus neutrophil chemotaxis, Phagocytosis and killing are also weakened, so burns are prone to concurrent infection

Method used

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  • Composition with functions of clearing heat and detoxicating and preparation method thereof
  • Composition with functions of clearing heat and detoxicating and preparation method thereof
  • Composition with functions of clearing heat and detoxicating and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0108] Burnet 7 parts, Rhubarb 50 parts, Scutellaria baicalensis 125 parts, Phellodendron 125 parts

[0109] 125 parts of Polygonum cuspidatum, 100 parts of Chuanxiong, 100 parts of Angelica dahurica, 100 parts of Asarum

[0110] 50 parts of honeysuckle, 50 parts of safflower, 20 parts of borneol

[0111] Burnet, rhubarb, skullcap, Phellodendron, Polygonum cuspidatum, Rhizoma Chuanxiong, Angelica dahurica, Asarum, honeysuckle and safflower are crushed into coarse powder, dipped in 30% ethanol once for 12 hours each time, collect the infusion, filter, and decompress Concentrate until medicinal material: water is about 1:1, concentrate under reduced pressure to obtain extract and dry, add borneol, appropriate amount of auxiliary materials, mix well, and make granules.

Embodiment 2

[0113] Burnet 175 parts Rhubarb 2 parts Scutellaria baicalensis 125 parts Phellodendron 125 parts

[0114] 125 parts of Polygonum cuspidatum, 100 parts of Chuanxiong, 100 parts of Angelica dahurica, 100 parts of Asarum

[0115] 50 parts of honeysuckle, 50 parts of safflower, 20 parts of borneol

[0116] Burnet, rhubarb, skullcap, Phellodendron, Polygonum cuspidatum, Rhizoma Chuanxiong, Angelica dahurica, Asarum, honeysuckle and safflower are crushed into coarse powder, dipped in 90% ethanol twice for 24 hours each time, collect the infusion, filter, and depressurize Concentrate until the medicinal material: water ratio is about 3:1, concentrate under reduced pressure to obtain an extract and dry, add borneol, appropriate amount of auxiliary materials, mix well, and press into tablets to obtain.

Embodiment 3

[0118] 175 parts of Burnet, 50 parts of Rhubarb, 5 parts of Scutellaria, 125 parts of Cortex Phellodendri

[0119] 125 parts of Polygonum cuspidatum, 100 parts of Chuanxiong, 100 parts of Angelica dahurica, 100 parts of Asarum

[0120] 50 parts of honeysuckle, 50 parts of safflower, 20 parts of borneol

[0121] Burnet, rhubarb, skullcap, Phellodendron, Polygonum cuspidatum, Rhizoma Chuanxiong, Angelica dahurica, Asarum, honeysuckle, and safflower are crushed into coarse powder, soaked in 40% ethanol for 3 times, each time for 60 hours, collect the infusion, filter, and decompress Concentrate until the medicinal material: water ratio is about 2:1, concentrate under reduced pressure to obtain an extract and dry, add borneol, appropriate amount of auxiliary materials, mix well, fill in capsules, and obtain.

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Abstract

The invention discloses a traditional Chinese medicine composition with the functions of clearing heat and detoxicating and a preparation method thereof. The composition is the clinically-acceptable formulation prepared by using garden burnet, rheum officinale, scutellaria baicalensis, golden cypress, giant knot weed, ligusticum wallichii, radix angelicae, asarum, honeysuckle, red flower and borneol as the materials and processing the materials by different physical or chemical methods according to the different physicochemical properties of effective components in the traditional Chinese medicines. The invention has special formulation and can be used in clinic for treating soft tissue injury, skin injury and burn with remarkable effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition with the function of clearing away heat and detoxifying, in particular to a composition with the function of clearing away heat and detoxifying which is prepared from Chinese herbal medicines as raw materials. Background technique [0002] Soft tissue injury and skin trauma are frequently-occurring and common diseases in the Department of Orthopedics and Traumatology, which belong to the category of "muscle injury" in the dialectical medicine of the motherland. Divided into acute and chronic conditions. Acute injury is caused by external violent effects such as acute falls, beatings, twists, and frustrations. Chronic injuries refer to the fatigue injuries of joints, cartilage, muscles, tendon sheaths, ligaments, synovium and other tissues, and are more common than acute injuries, mainly because the affected soft tissues are affected by long-term, concentrated, repeated, and powerful p...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61P17/00A61P17/02A61P29/00A61K31/045
Inventor 曹龙祥董自波陆步实
Owner 江苏天济药业有限公司
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