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Drug delivery implants for inhibition of optical defects

A technology of implants and drugs, applied in the direction of eye implants, drug combinations, sensory diseases, etc., can solve problems such as difficulty in use, side effects, and disease development

Inactive Publication Date: 2009-12-30
QLT INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, using atropine eye drops has side effects and needs to be used regularly for an extended period of time
In addition, eye drops are difficult to administer in children, making compliance a prominent issue in treatment
As mentioned above, in the treatment method with eye drops, compliance may be the decisive factor in achieving the desired clinical effect, and leakage of eye drops may lead to further development of the disease

Method used

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  • Drug delivery implants for inhibition of optical defects
  • Drug delivery implants for inhibition of optical defects
  • Drug delivery implants for inhibition of optical defects

Examples

Experimental program
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Effect test

Embodiment Construction

[0052] Picture 1-1 and 1-2 It is a schematic diagram of the anatomical structure of the implant suitable for the eye according to the embodiment of the present invention. Eye 2 includes cornea 4 and iris 6 . The sclera 8 surrounds the cornea 4 and the iris 6 and is white. The conjunctival layer 9 is very transparent and wraps around the sclera 8 . The lens 5 is located in the eye. The retina 7 is located at the back of the eye 2 and is normally sensitive to light. The retina includes the macula 7F, which provides the sharpest vision and color vision. Cornea 4 and lens 5 can refract light to make it image on macula 7F and retina 7 . The refractive power of the cornea 4 and lens 5 contributes to the imaging on the macula 7F and retina 7 . The relative positions of the cornea 4, lens 5 and macula 7F are also important for the quality of the image. For example, if the axis of the eye 2 from the cornea 4 to the retina 7F is elongated, the eye 2 may be myopic. Also, when a...

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Abstract

An implant for use with an eye comprises an implantable structure and a therapeutic agent. The therapeutic agent is deliverable from the structure into the eye so as to therapeutically effect and / or stabilize a refractive property of the eye. In many embodiments, the refractive property of the eye may comprise at least one of myopia, hyperopia or astigmatism. The therapeutic agent can comprise a composition that therapeutically effects or stabilizes the refractive property of the eye. The therapeutic agent may comprise at least one of a mydriatic or a cycloplegic drug. For example, the therapeutic agent may include a cycloplegic that comprises at least one of atropine, cyclopentolate, succinylcholine, homatropine, scopolamine, or tropicamide. In many embodiments, a retention element can be attached to the structure to retain the structure along a natural tissue surface.

Description

[0001] Refer to related application [0002] This application claims the benefit of US Provisional Patent Application No. 60 / 871,867, filed December 26, 2007, the specific publication of which is incorporated herein by reference. Background technique [0003] The present invention treats visual defects in the eye using an implant that releases one or more therapeutic agents. [0004] The pathological circumstances of vision loss can be disabling. The optical defects of the eyes interfere with people's ability to see things. The degree of influence is almost imperceptible, and the severe one can cause blindness. A common form of visual defect in the eye is a refractive error of the eye, typically including nearsightedness, hyperopia and astigmatism. Refractive errors of the eye are usually caused by imperfections in the physical properties of the ocular tissues so that they are not ideally imaged on the retina. The front of the eye has the surface of the cornea and the lens...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/14A61M31/00A61M35/00A61B18/18
CPCA61F9/00781A61F9/00772A61F9/0017A61K9/0051A61P27/02A61M31/00A61F2/142A61M35/00A61P27/10A61P27/06A61P27/04A61P27/08
Inventor 尤金·小德胡安斯蒂芬·博伊德卡里·赖克
Owner QLT INC
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