Degradable blood vessel casting agent
A casting and blood vessel technology, applied in the field of bioengineering, can solve the problems such as the difficulty of preparing tissue engineering scaffolds with a blood vessel casting agent, and achieve the effects of good mechanical and physical properties, good compatibility and excellent plasticity
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Embodiment 1
[0019] Take 1.0 gram of poly D, L lactic acid with a molecular weight of 390,000, put it in a beaker, add 10 ml of ethyl acetate, and after the poly D, L lactic acid is completely dissolved, the polylactic acid casting agent is obtained. Can be used as a vascular cast.
[0020] Use this casting agent to cast liver blood vessels in rats, then cut off the liver and let it dry naturally at room temperature, then put it in 25% hydrochloric acid solution for 3 days, wash it slowly with running water, remove cells and connective tissue, and then wash it with soap After soaking in water for 1 day, a milky white rat liver vascular tree model is obtained. its photo see figure 1 .
Embodiment 2
[0022] Take 2.0 grams of polyglycolic acid and place it in a beaker, add 10 ml of acetone, and after the polyglycolic acid is completely dissolved, the polyglycolic acid casting agent is obtained. Can be used as a vascular cast.
Embodiment 3
[0024] Take 0.5 g of poly D, L lactic acid and 0.5 g of polyglycolic acid and put them in a beaker, add 5 ml of chloroform, 1,4 dioxane, after the poly D, L lactic acid and polyglycolic acid are completely dissolved, the poly D, L lactic acid and polyglycolic acid casting agents can be used as vascular castings.
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