Pharmaceutical composition containing beta2 agonists and steroids, and uses thereof
A technology of β2 receptors and compositions, applied in the direction of drug combination, drug delivery, medical preparations containing active ingredients, etc.
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Embodiment 2
[0027] Example 2 - Inhalation powder aerosol
[0028]
[0029] Preparation process: tetrabuterol hydrochloride or mapbuterol hydrochloride and fluticasone propionate are respectively ground into powder with a particle size of 5 μm through a supersonic jet mill at high speed. The medicinal carrier lactose is pulverized into a powder with a particle size of 120 μm by the main machine of the horizontal air-sorting pulverizer, and then the same amount of ultrafine dry powder of the above-mentioned tetrabuterol hydrochloride or mapbuterol hydrochloride and the medicinal carrier is prepared. Incrementally mix well and fill in capsules.
Embodiment 3
[0031]
[0032] Preparation process: tetrabuterol hydrochloride or mapbuterol hydrochloride and fluticasone propionate are respectively ground into powder with a particle size of 5 μm through a supersonic jet mill at high speed. The medicinal carrier lactose and poloxamer are pulverized into a powder with a particle size of 120 μm by a ball mill, and then the superfine dry powder of the above-mentioned tetrabuterol hydrochloride or mapbuterol hydrochloride and the medicinal carrier is prepared by equal increment method. Mix well and fill in capsules.
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