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Antineoplastic isoliquirtigenin tablet

An isoliquiritigenin and anti-tumor technology, which is applied in the directions of anti-tumor drugs, pill delivery, drug combination, etc., to achieve the effects of safe use, convenient administration, and simple and easy production process

Inactive Publication Date: 2008-04-02
WUHAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] 2. Currently, there are many methods for treating tumors, but all of them have certain limitations
[0010] But, so far, no preparation method of oral preparations such as isoliquiritigenin anti-tumor tablets or capsules is disclosed or used after retrieval.

Method used

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  • Antineoplastic isoliquirtigenin tablet
  • Antineoplastic isoliquirtigenin tablet
  • Antineoplastic isoliquirtigenin tablet

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0039] Embodiments of the present invention will be described below, but the content of the present invention is not limited thereto at all.

[0040] Isoliquiritigenin

filler

Adhesive

disintegrant

D

lubricant

Example 1

10.0%

starch

85.0%

gum arabic

2.0%

Croscarmellose Sodium

1.0%

ethanol

1.0%

Magnesium stearate

1.0%

Example 2

10.5%

Dextrin

84.0%

Hydroxymethyl Cellulose

2.0%

Sodium carboxymethyl starch

1.5%

ethanol

1.0%

polyethylene glycol

1.0%

Example 3

11.0%

starch

83.0%

gum arabic

3.0%

Hydroxypropyl starch

1.0%

ethanol

1.0%

polyethylene glycol

1.0%

Example 4

11.5%

Dextrin

81.0%

gelatin

1.0%

Sodium carboxymethyl s...

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PUM

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Abstract

The invention discloses an antitumor isoliquiritigenin tablet. The isoliquiritigenin is used as an effective component to prepare antitumor tablet. The antitumor isoliquiritigenin tablet contains isoliquiritigenin, filler, adhesive, disintegrant, wetting agen and lubricant, which are proportioned according to a certain proportion. The formula is reasonable and the use is convenient. The drug combination prepared in the method has good antitumor function, good treating effects and low side effects.

Description

technical field [0001] The invention relates to the field of pharmacy, in particular to an anti-tumor isoliquiritigenin tablet. Suitable for human cervical cancer cells, prostate cancer cells, S 180 Tumor lines, Ehrlich ascites cancer cells, human A549 lung cancer cells, oral epidermal cancer KB cells, KM-12 colon cancer cells, BEL-7402 liver cancer cells and MCF-7 breast cancer cells. Background technique [0002] 1. Tumor has become the number one killer threatening human health [0003] Tumor is one of the common and frequently-occurring diseases that seriously threaten human life, and its incidence rate is increasing year by year. According to the survey of the World Health Organization, nearly 10 million cancer patients are newly discovered every year in the world. Nearly 7 million people die from cancer every year. Recent statistics show that about 20 million cancer patients are newly discovered in my country every year, and nearly 1.5 million people die of cancer....

Claims

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Application Information

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IPC IPC(8): A61K31/12A61K9/20A61K47/40A61P35/00
Inventor 杨静周倩朱玲新李颖程昊敖英刘洋陈刚
Owner WUHAN UNIV
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