Application of traditional Chinese medicine preparation in preparing medicine for treating and preventing gynaecologic disease

A technology for traditional Chinese medicine preparations and gynecological diseases is applied in the field of use of traditional Chinese medicine preparations in the preparation of medicines for the treatment and prevention of gynecological diseases, which can solve the problems of increasing the risk of breast cancer and the like, and achieve the effects of remarkable curative effect and convenient taking.

Active Publication Date: 2007-11-28
SHANGHAI HONGYITANG BIOPHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Another study shows that if women take estrogen for a long time, resulting in higher levels of estrogen in the body, the risk of breast cancer caused by hormones increases by 48%

Method used

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  • Application of traditional Chinese medicine preparation in preparing medicine for treating and preventing gynaecologic disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] Soak 146 grams of Astragalus membranaceus, 195 grams of Codonopsis pilosula, 196 grams of Atractylodes macrocephala, 98 grams of angelica, 90 grams of Chuanxiong, 49 grams of Bupleurum, 90 grams of Wang Buliuxing (fried), 87 grams of leaking reed, 49 grams of Hemerocallis root, add 7 kg of water and soak for 20 After 1 hour, heat and boil for 3 hours, filter out the medicinal liquid; add 7 kg of water to the medicinal residue, heat and boil for 0.5 hour, and filter out the medicinal liquid; add 4 kg of water to the medicinal residue, heat and boil for 2 hours, combine the water extracts for 3 times, and filter Concentrate under reduced pressure to an extract with a relative density of 1.10 g / ml at 80°C, and cool to room temperature for later use.

[0062] Take 480g of crushed sucrose powder passed through a 80-mesh sieve, 420g of dextrin passed through a 120-mesh sieve, mix in a blender, add the above extract under stirring, continue to stir to form a suitable soft mater...

Embodiment 2

[0064] Soak 250 grams of astragalus, 146 grams of Codonopsis pilosula, 120 grams of Atractylodes macrocephala, 120 grams of angelica, 49 grams of Chuanxiong, 60 grams of Bupleurum, 73 grams of Wangbuliuxing (fried), 102 grams of leaking reed, 80 grams of Hemerocallis root, add 6.5 kilograms of water and soak for 10 After 1 hour, heat and boil for 2 hours, filter out the medicinal liquid; add 3.25 kg of water to the medicinal residue, heat and boil for 3 hours, and filter out the medicinal liquid; add 3.9 kg of water to the medicinal residue, heat and boil for 1 hour, combine the water extracts for 3 times, and filter Concentrate under reduced pressure to an extract with a relative density of 1.30 g / ml at 80°C, and cool to room temperature for later use.

[0065] With reference to the method of Example 1, a capsule preparation of 0.25 g / granule was prepared according to a conventional method.

Embodiment 3

[0067] Soak 166 grams of astragalus, 300 grams of Codonopsis pilosula, 98 grams of Atractylodes macrocephala, 140 grams of angelica, 146 grams of Chuanxiong, 100 grams of Bupleurum, 110 grams of Wangbuliuxing (fried), 82 grams of leaking reed, 60 grams of Hemerocallis root, add 15 kilograms of water and soak for 2 After 1 hour, heat and boil for 2.5 hours, filter out the medicinal liquid; add 10 kg of water to the medicinal residue, heat and boil for 1 hour, and filter out the medicinal liquid; add 8.5 kg of water to the medicinal residue, heat and boil for 0.5 hour, combine the water extracts for 3 times, and filter Concentrate under reduced pressure to an extract with a relative density of 1.50 g / ml at 80°C, and cool to room temperature for later use.

[0068] Add 1000 grams of water to dissolve the extract, add 480 grams of glucose and 420 grams of starch and mix, and adopt the method of spray drying to obtain the granular prolactin granules of the present invention.

[006...

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Abstract

The present invention discloses one kind of Chinese medicine preparation and its use. The Chinese medicine preparation is prepared with astragalus root, Dangshen, white atractylodes rhizome, angelica, Chuanxiong rhizome and other four kinds of Chinese medicinal materials in certain weight proportion. It is prepared into different kinds of solid oral preparations through soaking the Chinese medicinal materials, water extracting, filtering, concentrating to obtain extractum, adding supplementary material and other steps. The Chinese medicine preparation is used in treating mastoproliferation and hysteromyoma, and preventing and treating mammary cancer.

Description

field of invention [0001] The invention relates to the application of a traditional Chinese medicine preparation in the preparation of medicines for treating and preventing gynecological diseases, in particular the application of medicines for treating hyperplasia of mammary glands, hysteromyoma and preventing and treating breast cancer. Background technique [0002] Mammary gland hyperplasia, also known as "mammary gland dysplasia", is pathologically manifested as an increase in lobular ducts and acini, interstitial connective tissue hyperplasia, etc., forming a series of pathological changes, resulting in changes in the internal blood supply of the mammary gland. It is a common and frequently-occurring disease in adult women. In recent years, it has been believed that hyperplasia of mammary glands is one of the important factors for the onset of breast cancer, especially in the atypical hyperplasia stage of hyperplasia of mammary glands, which is a precancerous lesion of br...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K9/08A61K9/10A61K9/16A61K9/20A61K9/48A61P15/00A61P15/14A61P35/00
Inventor 高尚先
Owner SHANGHAI HONGYITANG BIOPHARM CO LTD
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