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Lamiophlomis-rotata leaf-stem distract and its preparing process and use

A unique and extractive technology, applied in medical preparations containing active ingredients, drug delivery, drug combination, etc., can solve the problems of resource destruction, ecological environment damage, prolonged harvesting period, etc., and shorten the harvesting period. Cycle, protect the ecological environment, less toxic and side effects

Inactive Publication Date: 2007-08-29
刘梅
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Because the unique flavor is distributed in the plateau area of ​​2700-4500 meters, it is a perennial herb that grows slowly. Excavating the whole herb will cause devastating damage to the unique resources and seriously damage the local ecological environment; even if you plant it yourself, because of It grows slowly and has a long growth cycle, and it can be harvested for medicinal use after many years; when the whole plant is collected, after the root is excavated, the plant cannot grow again, and it will happen that it will be planted once harvested, which makes the harvest cycle significantly longer. Prolonged, the economic benefit is obviously reduced

Method used

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  • Lamiophlomis-rotata leaf-stem distract and its preparing process and use
  • Lamiophlomis-rotata leaf-stem distract and its preparing process and use
  • Lamiophlomis-rotata leaf-stem distract and its preparing process and use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0074] Take 100kg of stems and leaves of Duyiwei, add 800kg of water, boil and extract for 1 hour, filter, and the filtrate is set aside, add 700kg of water to the medicinal residue, boil and extract for 1 hour, filter, combine the filtrate twice, and concentrate the combined filtrate to a relative density of About 1.08 dilute extract, pass this dilute extract through D101 macroporous adsorption resin column, first elute with water until colorless, discard the water eluate, then elute with 85% ethanol until colorless, collect this 85% ethanol eluate, the 85% ethanol eluate after recovering ethanol is concentrated into a thick extract with a relative density of about 1.11, and the thick extract is spray-dried to obtain a unique stem containing about 10% flavonoids leaf extract.

Embodiment 2

[0076] Take 100kg of unique herbs, add 900kg of water, boil for 2 hours, filter, and use the filtrate for later use, add 900kg of water to the dregs, boil and extract for 1 hour, filter, combine the two filtrates, and concentrate the combined filtrate to a relative density of about 1.05, add ethanol until the ethanol content is 40%, let it stand for 18 hours, take the supernatant, recycle the ethanol from the supernatant into a dilute extract with a relative density of about 1.02, and pass the dilute extract through D201 macroporous adsorption resin , first eluted with 15% ethanol until colorless, discarded the 15% ethanol eluate, then eluted with 60% ethanol until colorless, collected the 60% ethanol eluate, and recovered 60% ethanol Concentrate the ethanol eluate into a thick extract with a relative density of about 1.10, dry the thick extract under reduced pressure, add 5 times the amount of water, heat to dissolve, then add n-butanol to extract 3 times, each time n-butanol ...

Embodiment 3

[0078] Take 100kg of unique herbs, add 1000kg of water, boil for 2 hours, filter, and use the filtrate for later use, add 900kg of water to the dregs, boil and extract for 1 hour, filter, add water to the filtrate, add 900kg of water to the dregs, boil for 1 hour, and filter , combined the three filtrates, concentrated the combined filtrate to a relative density of about 1.05, added ethanol until the ethanol content was 95%, left it for 24 hours, took the supernatant, and recovered the ethanol from the supernatant to a relative density of about 1.05 The dilute extract, the dilute extract was passed through D201 macroporous adsorption resin, first eluted with 20% ethanol until colorless, discarded the 20% ethanol eluate, and then eluted with 50% ethanol until colorless, Collect this 50% ethanol eluate, concentrate the 50% ethanol eluate after recovering ethanol into a thick extract with a relative density of about 1.09, dry the thick extract under reduced pressure to obtain flav...

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Abstract

The present invention discloses a Chinese medicinal plant lamiophlomis rotate stem and leaf extract, its preparation process and its application. Said extract mainly contains flavone component, and the pharmacodynamic tests show that said lamiophlomis rotata stem and leaf extract has the actions of stopping pain, resisting inflammation and promoting blood circulation.

Description

Technical field [0001] The invention relates to a traditional Chinese medicine extract, in particular to an effective part extracted from the stem and leaf of the unique traditional Chinese medicine. The invention also relates to the preparation method and application of the traditional Chinese medicine extract. Background technique [0002] Duyiwei is mainly distributed in the middle, east and surrounding mountains of the Hengduan Mountains in the southwest and northwest of my country. It is often found in the sparse vegetation of alpine meadows, grassland irrigation, river beaches and alpine rocky beaches at 2700-4500 meters. Among them, the unique distribution area is the largest in the alpine meadow, and the sparse vegetation in the alpine flowstone beach is the smallest. [0003] The national standard Chinese Pharmacopoeia 2005 edition one page 184 stipulates that the unique taste is the dry whole herb of Lamiophlomis rotata (Benth.) Kudo. Medicinal parts include root...

Claims

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Application Information

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IPC IPC(8): A61K36/53A61K9/00A61P29/00A61K127/00A61K135/00
Inventor 刘梅李文军
Owner 刘梅
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