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Medicine for improving immunity and treating malignant tumour and preparation process thereof

A technology for malignant tumors and immunity, which is applied in the field of drugs for the treatment of malignant tumors. It can solve the problems of inability to completely remove viruses in the body, easily produce adverse reactions, and limit the application of drugs, so as to improve human immunity, improve the body's immunity, and achieve obvious curative effects. Effect

Inactive Publication Date: 2007-08-15
张石泉
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For the treatment of malignant tumors, there are still no curable drugs in the world. Most of the drugs currently used for treatment are chemical drugs. Although they can relieve symptoms and prolong the course of the disease, there are still many problems: the virus in the body cannot be completely eliminated, and the drug rebounds. Adverse reactions are easy to occur, side effects are large and treatment costs are high, which greatly restricts the application of these drugs, so traditional drugs with low toxicity, effectiveness and low price, especially traditional Chinese medicine, have attracted much attention at home and abroad.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A drug for improving the body's immunity and treating malignant tumors. The active ingredient contained in it is F-glycoside peptide. F-glycoside peptide is the effective part of the single traditional Chinese medicine kelp, and it is a sulfuric acid-containing Ester group protein polysaccharide, its main physical and chemical characteristics are: easily soluble in water, solubility ≥ 30%, white or yellow polycrystalline powder, with special fragrance; SO 4 2- The content is 20±5%, the fucose content is 20±5%, and the protein content is 10-18%.

[0028] The preparation method of the medicine includes the following steps of producing and extracting the F-glycoside peptide: 100kg of seaweed is soaked, washed, crushed, added with 800kg of water, and extracted three times at 90-100°C for 3.5 hours. The supernatant was concentrated under reduced pressure to 25 L, precipitated under 30% ethanol, then the supernatant was evaporated to 10 L under reduced pressure, added to 85 ...

Embodiment 2

[0030] The clinical data and application methods of drugs for the treatment of malignant tumors are as follows:

[0031] (1) Case selection

[0032] All 189 patients met the following conditions, (1) confirmed by pathological or histocytological diagnosis. (2) Activity status score (Karnofsky) ≥ 60 points, estimated survival time > 3 months. (3) No serious heart, liver, kidney and other diseases, and the blood picture, liver and kidney functions are within the normal range. (4) Stage I~IV gastric cancer, lung cancer, and esophageal cancer.

[0033] (2), grouping

[0034] Before treatment, 189 patients were randomly divided into treatment group and control group by envelope method according to different parts. The treatment group (chemotherapy + F-glycoside peptide) included 96 cases (including 33 cases without surgery), including 35 cases of lung cancer, 30 cases of gastric cancer, and 31 cases of esophageal cancer. The control group (chemotherapy or radiotherapy alone) i...

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Abstract

This invention relates to a medicine for improving immunity and treating malignant tumor and its preparation method, and belongs to the technology field of preparing medicine for treating malignant tumor. The medicine is characterized in comprising the active constituent of F-Glycocalyx which is the valid target of ecklonia kurome and is protein polysaccharides containing sulfate group extracted from ecklonia kurome. the preparation method of F-Glycocalyx comprise (1) selecting, (2) soaking and cleaning, (3) pulverizing, (4) extracting with water, (5) precipitating with alcohol of low concentration, (6) precipitating with alcohol of high concentration, and (7) purifying to obtain purified product, drying, and packaging. The inventive medicine can effectively inhibit malignant tumor viral, improve immunity with no toxicity and adverse side effect, no untoward reaction and low cost.

Description

1. Technical field [0001] The invention relates to a drug for improving body immunity and treating malignant tumors and a preparation method thereof, belonging to the technical field of drugs for treating malignant tumors. 2. Background technology [0002] Malignant tumors caused by weakened immunity of the body are a disease with high morbidity and high mortality. At present, the annual incidence of malignant tumors in my country is increasing year by year, and countless patients die of malignant tumors every day, which brings great pain to patients and their families. For the treatment of malignant tumors, there are still no curable drugs in the world. Most of the drugs currently used for treatment are chemical drugs. Although they can relieve symptoms and prolong the course of the disease, there are still many problems: the virus in the body cannot be completely eliminated, and the drug rebounds. Adverse reactions are easy to occur, side effects are large and treatment c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/16A61K36/02A61K9/08A61K9/20A61K9/48A61P37/04A61P35/00A61K127/00
Inventor 张石泉
Owner 张石泉
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