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Method for preparing Duzhong soft capsule rich in alpha-linolenic acid and effective component of bark of eucommia

A technology of linolenic acid and soft capsules, which is applied in the field of preparation of Eucommia soft capsules, can solve the problems of soft capsules that need to be improved, low active ingredient content, poor efficacy, single perilla seed oil or Eucommia seed oil, etc., and achieve prevention Alzheimer's disease, efficacy improvement, effect of prevention of cerebral thrombosis and myocardial infarction

Active Publication Date: 2007-07-25
NORTHWEST A & F UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Aiming at the problems that the content of active ingredients in Eucommia leaf health food is low, the effect is not good, and the efficacy of single perilla seed oil or Eucommia seed oil soft capsule needs to be improved, the purpose of the present invention is to provide a kind of enhanced perilla seed oil (or Eucommia ulmoides seed oil) Seed oil) and the preparation method of Eucommia soft capsule product of Eucommia efficacy

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0021] The preparation method of Eucommia ulmoides soft capsules rich in alpha-linolenic acid and eucommia ulmoides active ingredients of the present invention includes 9 processes including leaf picking, sorting, leaching, extraction, concentration, drying, pulverization, batching, and soft gum filling. The process, the specific steps are:

[0022] 1. Cleaning steps: cleaning the raw materials of Eucommia ulmoides green leaves to remove impurities.

[0023] 2. Leaching step: rinse the cleaned eucommia green leaf raw materials to wash off dust and soil.

[0024] 3. Extraction step: Put the leaves of Eucommia ulmoides after the water has been drenched into the extraction tank. Heat reflux extraction twice; extraction time: 1 hour each time; extraction temperature: 80°C; solvent name: edible alcohol; solvent dosage: the amount of solvent used for the first extraction is 10 times the weight of Eucommia leaves (alcohol concentration is 75 %), the amount of solvent used in the second e...

Embodiment 1

[0033] Take 30kg eucommia leaves, after cleaning and leaching, put the eucommia leaves leached from the water into an extraction tank, add 10 times the amount of 75% by mass of edible alcohol, and then reflux and extract at 80°C 1 hour (to extract the total flavonoids of Eucommia ulmoides), filter, and take the filtrate. Then, add 8 times the amount of 40% by mass of edible alcohol to the filter residue, then reflux and extract for 1 hour at 80° C. (to extract the total eucommia glycosides), filter, and take the filtrate. The extract is concentrated under reduced pressure, and the extract is dried by a traditional drying method, and 3.6 kg of dry extract powder is obtained after drying (dry extract moisture content: ≤8%). The dry extract is immediately put into a sterile container, sealed, and the dry extract is crushed in a clean production area with a cleanliness of 100,000 to obtain dry extract powder. And the dry extract powder 3.6kg and perilla seed oil 3.6kg (using tradition...

Embodiment 2

[0035] Take 30kg of Eucommia ulmoides leaves, after sorting and leaching, put the leaves of Eucommia ulmoides drenched with water into the extraction tank, add 10 times the amount of 75% edible alcohol, and then reflux and extract 1 at 80℃ Hours (to extract the total flavonoids of Eucommia ulmoides), filter, and take the filtrate. Then, add 8 times the amount of 40% edible alcohol to the filter residue, then reflux for 1 hour at 80°C (to extract the total glycosides of Eucommia ulmoides), filter, and take the filtrate. The extract is concentrated under reduced pressure, and the extract is dried by a traditional drying method, and 3.6 kg of dry extract powder is obtained after drying (dry extract moisture content: ≤8%). The dry extract is immediately put into a sterile container, sealed, and the dry extract is crushed in a clean production area with a cleanliness of 100,000 to obtain dry extract powder. And the dry extract powder 3.6kg and eucommia seed oil 3.6kg (using traditional...

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Abstract

A softgel rich in alpha-linolenic acid and the active components of eucommia for decreasing blood pressure and blood fat and preventing cerebral thrombosis, myocardiac infarction, senile dementia, and cancer is prepared from eucommia leaf and the oil of perilla seed or eucommia seed through picking up leaves, removing impurities, leaching, extracting, concentrating, drying, pulverizing, mixing, and loading in softgels.

Description

Technical field [0001] The invention belongs to a manufacturing method in the field of food (health food), and specifically relates to a method for preparing a soft capsule of Eucommia ulmoides rich in alpha-linolenic acid and effective ingredients of Eucommia ulmoides. Background technique [0002] The main components in Eucommia ulmoides leaves are chlorogenic acid, aucubin, geniposide acid, flavonoids (quercetin and kaempferol) and more than 60 compounds. It has the effects of lowering blood pressure, lowering blood fat, anti-aging, strengthening immunity, anti-cancer and so on. [0003] Eucommia leaf extract products currently on the market (duzhong granules, eucommia capsules, eucommia tablets, etc.), due to the use of water extraction or single-concentration ethanol extraction methods, have low effective ingredient content; or are compatible with other medicinal plants, and are effective Although it has been enhanced, the effect is also not good. [0004] Perilla seed oil i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/46A61K36/536A61K9/48A61P3/06A61P9/12A61P35/00A61P37/04A61P39/06A61K127/00A61K131/00
Inventor 赵德义张康健任少龙王蓝马柏林高锦明董娟娥
Owner NORTHWEST A & F UNIV
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