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Toothpaste containing notoginseng extract and preparing method

The technology of extract and Panax notoginseng is applied in the field of toothpaste compositions, which can solve the problems of low effective components and unsatisfactory statistical effects, and achieve the effects of preventing periodontitis, obvious public health value and commercial value.

Active Publication Date: 2009-12-30
昆明牙膏有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Adding Panax notoginseng to toothpaste to improve the efficacy of its oral health medicine has attracted people's attention. The invention patent application No. 85106825 "Method and Application of Panax notoginseng Toothpaste Essence" is to dissolve 23 ingredients such as Panax notoginseng in ethanol and acetic acid by weight percentage Ethyl ester, alcoholized to prepare essence, but the active ingredient contained in Sanqi tincture is lower than that of extract, and the statistical effect in clinical trials is not very satisfactory

Method used

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  • Toothpaste containing notoginseng extract and preparing method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] formula:

[0018] Calcium carbonate 50%, sorbitol 15%, sodium carboxymethylcellulose 0.8%, carrageenan 0.5%, sodium lauryl sulfate 2%, essence 0.8%, saccharin 2%, Panax notoginseng liquid extract 0.07%, the rest for deionized water. Each 1ml of Panax notoginseng liquid extract is equivalent to 1.5g of the original drug.

[0019] Preparation:

[0020] Mix notoginseng liquid extract, friction agent, wetting agent, adhesive and foaming agent, send it into a three-in-one vacuum paste making machine, stir and grind at high speed for 25-40 minutes, and vacuum degas; add essence and stir again Grinding for 10 to 25 minutes and mixing evenly to obtain a toothpaste paste, which is filled and packed aseptically.

Embodiment 2

[0022] formula:

[0023] Calcium hydrogen phosphate 45%, glycerin 10%, propylene glycol 15%, xanthan gum 1%, guar gum 0.5%, sodium lauryl sulfate 2.5%, essence 0.8%, saccharin 2%, Panax notoginseng liquid extract 0.3% , the rest is deionized water. Each 1ml of Panax notoginseng liquid extract is equivalent to 1.5g of the original drug.

[0024] Preparation:

[0025] Put the notoginseng liquid extract, wetting agent and saccharin into deionized water and stir until the saccharin dissolves, mix with friction agent, adhesive and foaming agent, send it to a three-in-one vacuum paste machine, stir and grind at high speed for 25 ~ 40 minutes, vacuum degassing; add essence, and then stir and grind for 10 ~ 25 minutes to obtain toothpaste paste, aseptic filling and packaging.

Embodiment 3

[0027] formula:

[0028] 30% silicon dioxide, 15% sorbitol, 10% propylene glycol, 1% hydroxyethyl cellulose, 0.2% guar gum, 2% sodium lauryl sulfate, 1.2% essence, 2% saccharin, panax notoginseng Paste 0.5%, the rest is deionized water. Each 1ml of Sanqi fluid extract is equivalent to 1g of the original drug.

[0029] The preparation method is the same as in Example 2.

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PUM

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Abstract

The present invention relates to a toothpaste containing notoginseng extract and its preparation method. Its composition includes (by wt%) 0.07%-1.2% of notoginseng extract, 30%-55% of abrasive agent, 15%-30% of moistening agent, 0.6%-1.5% of binder and 2%-2.7% of foaming agent. Said toothpaste containing notoginseng extract has the health-care functions of preventing and curing the diseases of peridentitis, gingivitis, gingival bleeding and stomatocace, etc.

Description

technical field [0001] The present invention relates to oral health products, especially toothpaste compositions. Background technique [0002] Panax notoginseng (Burk.) F, H, Chen are Araliaceae ginseng plants, which have hemostatic, anti-inflammatory, analgesic and other effects, and are widely used in the prevention and treatment of various cardiovascular and cerebrovascular diseases. Panax notoginseng contains a variety of chemical components. Among them, the total saponin content of Panax notoginseng accounts for about 12% of the root tuber, which is the main active ingredient of Panax notoginseng. More than 20 A kind of monomeric saponins, including ginsenosides Rg1, Rg2, Rb1, Rb2, Rb3, Rc, Rd, Re, Rh, F2, notoginsenosides R1, R2, R3, R6, Fa, Fc, Fe, R4, etc. Notoginseng saponins are soluble in water and ethanol. Generally, higher concentrations of ethanol are used to extract saponins. Commonly used methods include dipping, percolation, and reflux extraction. Consider...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/97A61P11/00
Inventor 沈洋王富生李琼
Owner 昆明牙膏有限责任公司
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