Suppository of Chinese traditional medicine for improving intestine motivity and its preparation method

An intestinal motility and suppository technology, applied in the directions of suppository delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve the problems of affecting intestinal immune function and absorption function, easily destroying the intestinal environment, and gastrointestinal dysfunction, etc. Long-lasting drug effect, reducing intestinal adhesion and improving intestinal motility

Inactive Publication Date: 2008-05-14
包宗昭 +3
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Abuse of laxatives can easily damage the intestinal environment, affect intestinal immune function and absorption function, disturb gastrointestinal function or cause other adverse reactions
[0007] 3) Intestinal cleansing, before surgery, before colonoscopy, X-ray abdominal radiography, and angiography must be prepared for intestinal cleansing. Generally, serious medicines are used, and preparations must be made more than 12 hours in advance. Inappropriate for infirm or emergency patients;
[0019] Western medicine often uses phentolamine, alamin, neostigmine, scopolamine, dopamine, etc., and most of the above are injection drugs, which are inconvenient to use;
[0020] It has been reported that the traditional Chinese medicine Jiebi suppository is used to treat intestinal paralysis after abdominal surgery, but this medicine is not a marketed Chinese patent medicine

Method used

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  • Suppository of Chinese traditional medicine for improving intestine motivity and its preparation method
  • Suppository of Chinese traditional medicine for improving intestine motivity and its preparation method

Examples

Experimental program
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Effect test

Embodiment

[0083] Weigh the raw materials according to the following ratio:

[0084] Bupleurum 9.6kg Sophora flavescens 8kg Motherwort 8kg Citrus aurantium 9.6kg

[0085] Corydalis 8kg Radix Paeoniae Rubra 8kg Licorice 4.8kg

[0086] The production method is as follows:

[0087] The above seven herbs are cut or crushed into 10mm coarse grains, soaked in 10 times of water for 30 minutes. Heat and boil for 2 hours (collect and separate volatile oil components at the same time), filter, and collect the filtrate for the first time; add water 12 times for the second time, heat and boil for 2.5 hours to extract (collect and separate volatile oil components at the same time), filter; combine the first and second crude oils Filtrate, plate and frame filter press (two layers of silk cloth and three layers of filter paper). The fine filtrate is first decompressed and then concentrated under normal pressure; add 95% ethanol and stir to make the alcohol content reach 60%, stand still for 8 hours,...

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PUM

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Abstract

A Chinese medicine in the form of suppository for improving intestinal movement and treating abdominal distension and constipation is prepared from 7 Chinese-medicinal materials including bupleurum root, flavescent sophora root, motherwort, etc through choosing raw materials, proportioning, washing, breaking, immersing, heating, filtering, concentrating and shaping.

Description

1. Technical field [0001] The invention relates to a medicine for improving intestinal motility, specifically, a Chinese patent medicine prepared from Chinese herbal medicines as raw materials, and also relates to a preparation method of the medicine. 2. Background technology [0002] Postoperative abdominal distension and constipation are mostly intestinal motility disorders, mainly caused by weakened intestinal motility. Intestinal motility disturbance is a common pathophysiological mechanism of functional constipation, C-IBS, and colonic slow transit. [0003] 1) Postoperative abdominal distension is equivalent to postoperative temporary intestinal paralysis in Western medicine, which refers to those who have no anal exhaust after surgery, but have abdominal distension, abdominal pain, and intestinal peristalsis disappears or is weak. The main features of its pathological changes are the inhibition of intestinal peristalsis and the retention of digestive tract fluid. ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/75A61K9/02A61P1/10
Inventor 包宗昭吴大蓉杨晴光李长富
Owner 包宗昭
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