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Soft capsule of 'Sheng Mai' and preparation method thereof

A technology of soft capsules and Shengmai, which is applied in the field of pharmaceutical preparations, can solve the problems of low bioavailability, low stability, and large dosage, and achieve high bioavailability, accurate dosage, and good taste

Inactive Publication Date: 2010-05-19
徐国兵 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] Based on the prescription of Shengmaiyin, the formulations of Shengmaiyin that have been developed include Shengmai injection, Shengmaiyin oral liquid, and Shengmai capsule. The existing dosage forms and formulas are composed of some defects in use, such as Low stability, short storage period, low bioavailability, large dosage, etc. These problems need to be effectively solved

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Preparation of contents: Take 20g of Shengmaiyin extract fine powder, 75g of salad oil, and 5g of beeswax, mix them, heat to 80°C, stir and mix until uniform, make a suspension and keep it warm for later use.

[0043] Preparation of capsule shell: Take 2g of gelatin, 0.6g of glycerin, appropriate amount of water, mix well, heat to 70-80°C to melt, add appropriate amount of opacifying agent and coloring agent, stir and mix evenly, vacuumize, keep warm at 50°C for later use .

[0044] Preparation of soft capsules: the above-mentioned prepared contents and capsule shell materials are processed into soft capsules through a soft capsule machine, and then dried.

Embodiment 2

[0046] Preparation of the content: Take 16g of Shengmaiyin extract fine powder, 78g of salad oil, and 6g of beeswax, mix them, heat to 70°C, stir and mix until uniform, and make a suspension to keep warm for later use.

[0047] Preparation of the capsule shell: Take 2g of gelatin and mix with 0.5ml of water; take another 1g of sorbitol and mix with appropriate amount of water, heat to 46°C and melt, add the prepared gelatin solution, heat to 50°C under stirring, mix well and After vacuuming, keep warm at 50°C for later use.

[0048] Preparation of soft capsules: the above-mentioned prepared contents and capsule shell materials are processed into soft capsules through a soft capsule machine, and then dried.

Embodiment 3

[0050] Preparation of contents: Take 26g of fine powder of Shengmaiyin extract, 70g of soybean oil, and 4g of insect wax, mix them, heat to 80°C, stir and mix until uniform, and make a suspension to keep warm for later use.

[0051] Preparation of the capsule shell: Take 2g of gelatin and mix with 0.5ml of water; take another 1g of sorbitol and mix with appropriate amount of water, heat to 46°C and melt, add the prepared gelatin solution, heat to 50°C under stirring, mix well and After vacuuming, keep warm at 50°C for later use.

[0052] Preparation of soft capsules: the above-mentioned prepared contents and capsule shell materials are machined into soft capsules to obtain soft capsules, and then obtained after drying.

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PUM

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Abstract

The invention relates to soft capsules for restoring pulse beat and the process for preparing the capsules, wherein the effective constituents include red ginseng, lilyturf root and schisandra fruit extracts, and the contents also include oil solubility dispersing agent and suspension auxiliary agent. The advantages of the invention include convenient admission, easy carrying and high degree of hygiene.

Description

Technical field: [0001] The invention relates to the field of pharmaceutical preparations, in particular to Shengmai soft capsules and a preparation method thereof. Background technique: [0002] Shengmaiyin is derived from the ancient prescription Shengmaisan, which is a famous ancient prescription for nourishing qi and nourishing yin in traditional Chinese medicine. The prescription is composed of three medicines: ginseng, Ophiopogon japonicus, and Schisandra chinensis. Ginseng is sweet in nature and can nourish the middle and Qi, nourish the lungs and promote body fluid; Ophiopogon japonicus is sweet in nature, slightly bitter, and slightly cold, which can nourish yin and benefit the stomach, moisten the lungs and clear the heart. , so it is a good medicine for nourishing yin and nourishing yin; schisandra, sour and warm, has the effects of solidifying the surface and astringing sweat, astringing the lungs, nourishing the kidney and strengthening essence, promoting body f...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8968A61K36/57A61K36/258A61K9/48A61K47/44A61P9/10A61P9/06A61P9/04A61P9/02
Inventor 徐国兵陈卫东朱满洲陈卫鸿
Owner 徐国兵
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