Antibacterial nano-silver medical fibre, its production and use
A nano-silver antibacterial and nano-silver technology, which is applied in the field of medical materials, can solve the problem of unreasonable reaction components such as antibacterial materials, and achieve the effects of improving the preparation environment and the health of operators, preventing infection, and improving quality stability
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Embodiment 1
[0044] Preparation of Nanosilver Solution
[0045] Take 20~50mL 1×10 -3 mol / L AgNO 3The solution was heated and boiled for 10 minutes, slowly added dropwise 0.5-5mL of 1% sodium citrate solution under strong stirring, continued to boil for 10-15 minutes, and then distilled for 45 minutes, and the prepared silver sol was slowly cooled to room temperature, Dialysis and aging for 4 to 5 days.
Embodiment 2
[0047] Preparation of nano silver antibacterial medical fiber
[0048] a. Soak-squeeze-soak-squeeze the treated fiber under ventilated conditions, so that it can fully absorb the nano-silver solution.
[0049] b. Heat-treat the soaked fibers under ventilated conditions, and the fibers are attached with nano-silver particles.
[0050] c. Put the fibers obtained above into water, extrude and soak them, remove the water-soluble substances remaining in the threads, and then dry them to obtain the nano-silver antibacterial medical fibers of the present invention.
Embodiment 3
[0052] Broad-spectrum antibacterial activity of nano-silver antibacterial medical fiber
[0053] The antibacterial activity of the nano-silver antibacterial medical fiber (experimental group) prepared in Example 2 and the fiber without nano-silver particles (control group) was tested by plate detection method. The strains tested are listed in Table 1.
[0054] Sets of Erlenmeyer flasks, each containing an aliquot of the strain, were prepared by introducing the strains into Erlenmeyer flasks containing broth, and the tubes were incubated at 37°C for 18-24 hours. After the incubation, an aliquot of broth was taken from each Erlenmeyer flask and spread on trypticase casein soybean blood agar plate, the fibers of the present invention and the control were placed on the blood agar plate, and incubated at 37°C 18-24 hours.
[0055] The results showed that on the blood agar plates of the experimental group, no flora and signs of any growth were observed around the fibers of the exp...
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