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Chinese medicine effective part composition for supplementing qi and recovering pulse

A technology of effective parts, replenishing qi and rejuvenating the pulse, applied in the direction of drug combination, medical preparations containing active ingredients, antineoplastic drugs, etc., can solve the problem of long time boosting process, improving microcirculation effect and unfavorable pathology of acute and severe patients state and other problems, to achieve the effect of improved drug efficacy, significant curative effect, and rapid microcirculation effect

Inactive Publication Date: 2007-01-24
罗益民
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In modern clinics, Shenmai Injection is often used to treat shock and cardiovascular and cerebrovascular diseases, and it has a definite curative effect on patients with mild symptoms. However, modern pharmacological experiments and clinical applications have proved that Shenmai Injection can improve the pathological state mainly by strengthening the heart. , so the boosting process takes a long time, and the effect of improving microcirculation is moderate, which is not conducive to quickly improving the pathological state of acute and severe patients, and has obvious limitations in clinical first aid.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Embodiment one: the preparation of freeze-dried powder injection

[0042] Total Ginseng Saponins 25g

[0043] Cornel glycosides 75g

[0044] Mannitol 200g

[0045] Take total ginseng saponins, total glycosides of cornus and mannitol, add 2000ml water for injection, stir to dissolve, refrigerate and absorb with 0.1% activated carbon for 2 hours, filter, add water for injection to the filtrate to 5000ml, adjust pH to 6, filter, Packed into 1000 bottles, freeze-dried using the existing freeze-dried powder injection preparation process to obtain the freeze-dried powder injection of the present invention.

Embodiment 2

[0046] Embodiment two: take sodium chloride as the preparation of the large infusion solution of isotonic regulator

[0047] Total Ginseng Saponins 25g

[0048] Cornel glucosides 100g

[0049] Sodium chloride 900g

[0050] Sodium citrate 100g

[0051] Take total ginsenosides and total glycosides of cornus and mix them, add 5000ml of water for injection, stir to dissolve, refrigerate and absorb with 0.1% activated carbon for 2 hours, filter, and set aside. Take sodium chloride and sodium citrate, add 20000ml of water for injection, stir to dissolve, boil with 0.5% activated carbon for 15 minutes, filter, and set aside. Mix the above-mentioned filtrate, add water to 100000ml, adjust the pH to 7, filter, pack into 1000 bottles, and sterilize by autoclaving to obtain the large infusion solution of the present invention using sodium chloride as the isotonic regulator.

Embodiment 3

[0052] Embodiment three: the preparation of the big infusion solution that uses glucose as isotonic regulator

[0053] Total Ginseng Saponins 25g

[0054] Cornel glycosides 150g

[0055] Glucose 5000g

[0056] Sodium bisulfite 100g

[0057] Take total ginsenosides and total glycosides of cornus and mix them, add 5000ml of water for injection, stir to dissolve, refrigerate and absorb with 0.1% activated carbon for 2 hours, filter, and set aside. Take glucose, add 20000ml water for injection, stir to dissolve, boil with 0.5% activated carbon for 15 minutes, filter for later use. Mix the above filtrate, add water to 100000ml, add sodium bisulfite, adjust the pH to 5, filter, pack into 1000 bottles, and sterilize by autoclaving to obtain the large infusion solution of the present invention using glucose as the isotonic regulator.

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PUM

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Abstract

The present invention discloses a kind of Chinese medicine composition of effective components for supplementing qi and restoring pulse, and belongs to the field of medicine preparing technology. The medicine composition is prepared with total ginsenoside and total dogwood glycoside in certain weight ratio. The medicine composition has the functions of invigorating primodial qi, astringing qi, restoring pulse, etc. and is suitable for treating shock caused by different causes, multiple organ failure, coronary heart disease, etc.

Description

Technical field [0001] The invention belongs to the technical field of pharmacy, and relates to a composition of effective parts of traditional Chinese medicines for replenishing qi and rejuvenating the veins, in particular to a pharmaceutical composition made of total ginsenosides and total glycosides of cornus officinalis as raw materials. Background technique [0002] Shock and cardiovascular and cerebrovascular diseases are common clinical critical illnesses. Shock patients show symptoms such as fainting, significant drop in blood pressure, weak pulse, cyanosis, cold limbs, sweating, palpitations, etc., which are called "juetuo" and "jueni" in traditional Chinese medicine. Modern research proves that: tissue ischemia and hypoxia in shock patients lead to cell dysfunction, and at the same time, the blood is continuously concentrated, which promotes the aggregation of red blood cells and the formation of microthrombosis. Reperfusion injury, which in turn leads to multiple...

Claims

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Application Information

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IPC IPC(8): A61K36/40A61P9/10A61P9/04A61P9/06A61P9/02A61P7/02A61P3/10A61P35/00
Inventor 罗益民蔡炜
Owner 罗益民
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