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Chinese globe flower injection and preparation method thereof

A technology of injection and nasturtium, applied in the field of injection, can solve the problems of slow onset and long course of treatment, and achieve the effects of rapid onset of effect, shortened course of treatment and improved bioavailability

Inactive Publication Date: 2006-12-13
高春平
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are many common problems in oral Chinese medicine preparations at present: the treatment course of Chinese medicine is long and the onset is slow, because the destruction of the active ingredients of the medicine by the metabolic factors of the human body cannot be avoided

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Example 1: (1) Take 1 kg of nasturtium, add 10 kg of water, decoct for 0.5-2 hours, filter, add water to decoct the medicinal residues, repeat 2-5 times, combine the filtrates, concentrate under reduced pressure to contain nasturtium 1- 5g / ml;

[0023] Add ethanol to make the alcohol content reach 60-70%, let stand at 0-10°C for 20-60 hours, filter, recover ethanol under reduced pressure, and concentrate to contain nasturtium nasturtium 3-8g / ml;

[0024] Then add ethanol to make the alcohol content reach 75-85%, let stand at 0-10°C for 8-24 hours, filter, recover ethanol under reduced pressure, concentrate to contain nasturtium nasturtium 8-12g / ml;

[0025] Dilute with water to contain 3-5g / ml of nasturtium nasturtium;

[0026] (2) use macroporous resin for column packing and elution separation, eluent water and 30-50% ethanol are respectively the consumption of 2 times of macroporous resin, and ethanol eluent is collected;

[0027] (3) Recover the ethanol eluent unde...

Embodiment 2

[0033] The difference between embodiment 2 and embodiment 1 is as follows:

[0034] (1) Get 5 kg of nasturtium, add 75 kg of water; (2) The eluent water and 30-50% ethanol are respectively 8 times the amount of macroporous resin.

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PUM

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Abstract

The invention relates the globeflower injection and preparing method, comprising globeflower extract and active composition. The injection concentration is 10g globeflower per 10ml. The method comprises the following steps: 1 boiling the globeflower, filtering, decompressing thickening, adding ethanol, stewing, filtering, thickening; 2 diluting, separating with macroreticular resin; 3 adding the activated carbon into ethanol eluent, heating, stirring, filtering; 4 adjusting pH at 7.0-7.5, adding water to dilute, and getting the product. The invention has the advantages of improving the bioavailability and shortening the course of treatment.

Description

technical field [0001] The invention relates to an injection made from active ingredients extracted from Chinese herbal medicines, which is suitable for treating acute appendicitis, bacillary dysentery, upper respiratory tract infection, urinary system infection and the like. The invention also relates to a preparation method of the injection. Background technique [0002] Trollius is the dried flower of Trollius chinernsis bunge, a plant of Ranunculaceae. It is clinically used to treat acute appendicitis, bacillary dysentery, upper respiratory tract infection, urinary system infection, etc., with good curative effect and small side effects. Relevant data show that flavonoids are the main components of the antibacterial effect of nasturtium. The flavonoids contained in its organisms mainly include: orientin, vitexin and so on. At the same time, the ingredients with pharmacological effects include substances such as alkaloids. [0003] At present, the domestic existing ph...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61K9/08A61P11/00A61P1/12A61P13/00A61P31/04
Inventor 高春平
Owner 高春平
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