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A flexible retina chip and preparation method thereof

A retinal and flexible technology, applied in the field of flexible retinal chips and its preparation, can solve the problems of unfavorable circulation of retinal nutrients, limited flexibility of implant chips, and the inability to make through holes, etc.

Active Publication Date: 2006-12-13
HUAZHONG UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The flexibility of the entire implant chip is limited, which has greater damage to the retinal layer of the eye
In addition, since the power management unit, signal control, processing unit, stimulation current generation, distribution unit and other components are integrated on a single chip, the area of ​​the semiconductor sheet cannot be made very small (according to the patent, the diameter is 2-3mm ) This makes it impossible to make through holes in this area, which is not conducive to the circulation of nutrients between the upper and lower retinal cells in this part of the area

Method used

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  • A flexible retina chip and preparation method thereof
  • A flexible retina chip and preparation method thereof
  • A flexible retina chip and preparation method thereof

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Embodiment Construction

[0023] Such as figure 1 As shown in (a), (b) and (c), the structure of the flexible retinal chip of the present invention is: regularly distributed silicon islands 11 and through holes 33 are arranged between the top polymer film 31 and the bottom polymer film 32, The through holes 33 are distributed alternately with the silicon islands 11 , and a wiring layer 50 is arranged between the silicon islands 11 and the top polymer film 31 . The voids on the bottom polymer film 32 (that is, the positions except the silicon islands 11 , the through holes 33 and the wiring layer 50 ) are closely bonded to the top polymer film 31 , collectively referred to as the polymer film 30 .

[0024] Each silicon island 11 contains a functional unit 20 for simulating physiological functions. The functional unit 20 is processed by IC technology and MEMS technology, and it completes one or more of signal processing, control, photoelectric conversion or electrode stimulation functions. Several kinds...

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Abstract

The invention discloses the flexible retina chip. Between top layer polymeric film and bottom polymeric film there are silicon islands and via holes, in the silicon island there are function units which is used to simulate physiological function, and the between silicon island and top layer there is lead wire layer; bottom polymeric film is bonded with the top layer polymeric; the electric pole is on the top layer polymeric film or bottom polymeric film. The chip uses the MEMS technology to realize the integration of micro function unit and flexible basement. On the surface of the chip there are holes, so it is easy for nutriment and metabolite to exchange. The invention has the advantages of good biology function perfect ness, good metabolism, and improving the bending property and flexible of chip. The invention is used to high efficiency batch make.

Description

technical field [0001] The invention belongs to the technical field of medical instruments, and in particular relates to a flexible retina chip and a preparation method thereof. Background technique [0002] For blindness caused by retinal diseases such as macular degeneration, retinitis pigmentosa, and lesions of the lens and vitreous, retinal implants are a potentially effective means of restoring vision. Retinal implants can sense external light signals, undergo some specific signal processing, and generate electrical signal stimulation to stimulate optic nerve cells, thereby producing vision. A typical retinal implant includes three parts: 1) photoreceptor part; 2) signal processing part; 3) stimulation part. [0003] The prior art describes various forms of retinal implants. According to the difference of the chip implantation site, it can be divided into subretinal area implanter and supraretinal area implanter. They both provide specific forms of electrical stimula...

Claims

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Application Information

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IPC IPC(8): A61F2/14A61F9/00A61N1/05A61N1/36H01L21/82B81C1/00
Inventor 刘胜陆瑞毓张波甘志银张鸿海
Owner HUAZHONG UNIV OF SCI & TECH
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