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A medication for treating headache, and preparation method

A technology for drugs and raw materials, applied in the field of medicine, can solve the problems of poor oral administration, large dosage, and poor effect.

Active Publication Date: 2006-12-06
天士力东北现代中药资源有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The currently reported Chinese patent medicine for treating headaches is Zhengtian Wan, which is a combination of Chinese and Western medicines. Its mechanism is to promote blood circulation and remove blood stasis, and it is equipped with Western medicine analgesics. Internal injury headache, blood deficiency and blood stasis liver yang headache, the effect is not good
[0003] At present, there are many traditional Chinese medicines for treating headaches, and the dosage forms are mostly granules and granules. Granules have disadvantages such as slow dissolution rate, large dosage, poor taste when taken orally, and inconvenient taking and carrying.
For example, the date of application is 1993.1.9, the application number is 93100050.5, the authorized announcement number is CN1047938C, and the title of the invention is a patent application for a traditional Chinese medicine for treating headache. This invention provides a Chinese medicine granule for treating headache. Certain and easier to take than a decoction, but slower dissolution still limits its use

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Embodiment 1: the preparation of crude drug extract

[0048] Take 4-9g of angelica, 4-9g of Chuanxiong, 2-8g of white peony root, 2-8g of rehmannia glutinosa, 10-15g of Rhizoma Spatholobus, 10-15g of Spatholobus, 10-15g of Prunella vulgaris, 10-15g of cassia seed, and 10-10g of mother-of-pearl. 15g, Yuanhu 4~9g, Asarum 0.5~2g for later use;

[0049] The above eleven flavors, angelica, chuanxiong, white peony root, and corydalis are added with ethanol, heated to reflux, and the reflux liquid is stored in another container; the dregs and the other six flavors except Uncaria rehmanniae are decocted with water for three times. Add Uncaria uncariae, combine the decoction, concentrate under reduced pressure, add ethanol for alcohol precipitation, stand still, filter, combine the filtrate with the above-mentioned reflux liquid, recover ethanol under reduced pressure and concentrate the filtrate, dry to dry extract, and set aside.

Embodiment 2

[0050] Embodiment 2: the preparation of crude drug extract

[0051] Take 6.75g of Angelica, 6.75g of Chuanxiong, 5.4g of Radix Paeoniae Alba, 5.4g of Rehmannia Rehmanniae, 13.5g of Uncle Teng, 13.5g of Spatholobus Spatholobus, 13.5g of Prunella vulgaris, 13.5g of Cassia Seed, 13.5g of Mother of Pearl, 6.75g of Rhizoma Pediatricum, and Asarum 1.34g spare;

[0052] Add 70% ethanol to the above eleven flavors, angelica, Chuanxiong, white peony root, and Corydalis Corydalis, heat and reflux for 2 hours, and store the reflux liquid in another container; decoct the dregs and the other six flavors of rehmannia glutinosa except Uncaria chinensis three times, each time 1 hour, add Uncaria uncariae during the third decoction, combine the decoction, concentrate under reduced pressure to a relative density of 1.09-1.13 (55°C), add ethanol to make the alcohol content reach 65%, let stand for 24 hours, filter, The filtrate is combined with the above-mentioned reflux liquid, the ethanol is ...

Embodiment 3

[0053] Embodiment 3: the preparation of crude drug extract

[0054] Take Angelica 405.6g, Chuanxiong 405.6g, Paeoniae Alba 324.3g, Rehmannia glutinosa 324.3g, Uncaria 810.8g, Millipeda 810.8g, Prunella vulgaris 810.8g, Semen Cassiae 810.8g, Mother of Pearl 810.8g, Corydalis 405.6g, Asarum 80.8g spare;

[0055] Add 70% ethanol to the above eleven flavors, angelica, Chuanxiong, white peony root, and Corydalis Corydalis, heat and reflux for 2 hours, and store the reflux liquid in another container; decoct the dregs and the other six flavors of rehmannia glutinosa except Uncaria chinensis three times, each time 1 hour, add Uncaria uncariae during the third decoction, combine the decoction, concentrate under reduced pressure to a relative density of 1.09-1.13 (55°C), add ethanol to make the alcohol content reach 65%, let stand for 24 hours, filter, The filtrate is combined with the above-mentioned reflux liquid, the ethanol is recovered under reduced pressure and concentrated to a...

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PUM

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Abstract

A Chinese medicine in the form of dispersing tablet for treating headache is prepared from 11 Chinese-medicinal materials including Chinese angelica root, Chuan-xiong rhizome, white peony root, prunella spike, etc and proper auxiliaries including disintegrant, filler and lubricant. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a medicine for treating headache and a preparation method thereof. Background technique [0002] Headache is a common disease. Although some Chinese and Western medicines are available, the effect is not satisfactory, especially for the treatment of liver-yang headache of blood deficiency and blood stasis type. The curative effect of the medicine and the speed of onset of the medicine affect the patient key factor in quality of life. The commonly used Western medicine for the treatment of headaches has ergotamine caffeine, which is a vasodilator and is only suitable for cerebral arterial ischemic phlegm disease. The mechanism of action of flunarizine capsules produced in 1988 is to selectively inhibit the entry of calcium into cells to reduce the contraction of veins. The currently reported Chinese patent medicine for treating headaches is Zhengtian Wan, which is a combination of Chines...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61K9/20A61P25/04A61K35/618
Inventor 李永强郑永锋
Owner 天士力东北现代中药资源有限公司
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