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Gastroenteritis treating Chinese medicine preparation and its preparing process

A technology for traditional Chinese medicine preparations and gastroenteritis, which is applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, drug delivery, etc., can solve the problems of unfavorable storage of syrups, low content of active ingredients, complicated production operations, etc., and achieves high quality The effect of improving the control index, increasing the content of active ingredients and improving the stability of the drug

Active Publication Date: 2006-11-08
四川泰华堂制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Though this medicine has avoided the deficiency of above-mentioned antibiotic medicine, still there is following problem: because the dosage form of this medicine is syrup, uses adjuvant sucrose in a large amount, is unfavorable for the patient (especially diabetes patient) of avoiding sugar to take; In the preparation, a large amount of sucrose will be added, the production operation is complicated, and the microorganisms in the production environment are not easy to control; in addition, the syrup is not conducive to storage, and it is easy to produce secondary pollution after opening the bottle, which seriously affects the quality and stability of the drug; Yes, because the preparation is extracted by traditional methods, the content of active ingredients is low; in addition, the preparation has few quality control indicators, which cannot fully reflect and monitor the internal quality of the drug, and cannot guarantee to provide patients with products of uniform quality

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] (1) Take 66g of the medicinal materials Dijincao, 90g of the yellow hair ear, 66g of the camphor tree root, 33g of the fennel, and 33g of the maple leaves, and cut the medicinal materials after purification, and dry them; (2) add 10 times the amount of water to decoct twice, For 2 hours each time, combine the decoction, filter, and concentrate the filtrate directly to a clear paste with a relative density of about 1.2 (80°C), add 2 times the amount of ethanol, stir, stand still, ultrafiltration, and concentrate the filtrate to a relative density 1.07 or so (60 ℃) clear ointment; (3) add 0.09g stevioside, 0.01g essence and 0.5g sodium benzoate, stir well, filter; (4) add water to adjust the total amount to 100ml, fill it, and then take it orally Liquids and mixtures.

Embodiment 2

[0036] (1) Take 66g of the medicinal materials Dijincao, 90g of the yellow hair ear grass, 66g of the camphor tree root, 33g of the fennel, 33g of the maple leaves, 30g of the Pulsatilla chinensis, and 20g of the Phellodendron cork. Decoct in water three times, 2 hours each time, combine the decoction, filter, and after the filtrate is absorbed by the adsorption resin, wash away impurities with 5 times the amount of water, elute with 6 times the amount of 70% ethanol, collect the ethanol eluate, and elute The liquid is concentrated at 75°C to a clear paste with a relative density of 1.07 (60°C); (3) Add 0.1g aspartame, 0.2g essence, 0.1g sodium benzoate, 0.01g ethylparaben, stir well, and filter (4) Add water to adjust the total amount to 100ml, and fill it to obtain oral liquid and mixture.

Embodiment 3

[0038](1) Take 66g of the medicinal materials Dijincao, 90g of the yellow hair ear grass, 66g of the camphor tree root, 33g of the fennel, 33g of the maple leaves, 30g of the Pulsatilla chinensis, and 20g of the Phellodendron cork. Microwave extraction of water three times, each time for 0.5 hours, combined decoction, filtered, the filtrate was directly concentrated to a relative density of 1.22 (80°C), added 2 times the amount of ethanol, stirred, left to stand, ultrafiltration filtered, the filtrate was concentrated to a relative Clear paste with a density of 1.06 (60°C); (3) Add 4.8g of aspartame, 0.20g of essence and 0.03g of sorbic acid, stir well, and filter; (4) Add water to adjust the total amount to 100ml, pour Packing, that is, oral liquid and mixture.

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Abstract

The present invention discloses a kind of Chinese medicine preparation for treating acute and chronic gastroenteritis, diarrhea, bacillary dysentery and infantile indigestion and its preparation process. The Chinese medicine preparation is capsule or oral liquid prepared with wolfs milk, goldhair hedyotis herb, camphor root, elsoltzia and maple leaf, and into the material, Chinese pulsatilla root and phellodendron bark may be also added. Compared with available syrup, the present invention has the advantages of simple preparation process, high content of effective components, stable product quality, raised curative effect, etc.

Description

[technical field] [0001] The invention relates to a traditional Chinese medicine, in particular to a traditional Chinese medicine preparation for treating acute and chronic gastritis, enteritis, diarrhea, bacillary dysentery and dyspepsia in children and a preparation method thereof. [Background technique] [0002] Enteritis is a common disease and frequently-occurring disease. Although the mortality rate is not high, the incidence rate is high. The course of chronic enteritis can last for several years to decades, which seriously endangers people's health. However, antibiotics should not be taken for a long time. Improper use will cause intestinal flora imbalance and cause drug-induced diarrhea. [0003] In the 19th volume of "Prescriptions of Traditional Chinese Medicine", it is recorded that a prescription is composed of Dijincao, chrysanthemum, camphor root, fennel, and maple leaves, which are boiled and extracted into syrup Changyanning. The effect of clearing away hea...

Claims

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Application Information

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IPC IPC(8): A61K36/74A61K9/08A61K9/48A61P1/04
CPCY02A50/30
Inventor 俞凯
Owner 四川泰华堂制药有限公司
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