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Medicine composition of effective parts for compound Tongmai Chinese medicine oral liquid and its preparing method

A technology of effective parts and compositions, applied in the field of traditional Chinese medicine to prevent and treat chronic glomerular diseases, to achieve the effects of enhancing immune stability, significant curative effect, and reducing permeability

Inactive Publication Date: 2006-11-08
NO 2 CLINICO MEDICINE COLLEGE GUANGZHOU UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, the above two preparations have certain limitations in clinical use.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] The compound polysaccharide is extracted according to the following method: take 10 parts by weight of medicinal materials Astragalus and 3 parts of Radix Notoginseng, add 8 times the amount of water to soak for 24 hours, extract 2 times, extract 3 hours each time, filter, and filter each time The liquid phases were combined, then concentrated to 0.5g crude drug / ml, then added absolute ethanol until the alcohol content was 60%, left standing, overnight, poured out the supernatant, and the precipitate was washed successively with ethanol, acetone, ether until clean, 50 °C and dried to constant weight.

[0023] The compound saponin is extracted by the following method: take 10 parts by weight of the medicinal materials Astragalus membranaceus and 3 parts of Panax notoginseng, add 8 times the amount of water to soak for 24 hours, extract 2 times for 3 hours each time, and extract the liquid phase Combine, filter the extracts with gauze and cotton, store in the refrigerator...

Embodiment 2

[0026] The compound polysaccharide is extracted according to the following method: take 30 parts by weight of medicinal materials Astragalus, 9 parts of Radix Notoginseng, and 12 parts of Salvia Miltiorrhiza, add 18 times the amount of water to soak for 1 hour, extract 3 times, extract 1 hour each time, filter, Combine each filtrate, then concentrate to 0.1g crude drug / ml, then add absolute ethanol to 80% alcohol content, let it stand overnight, pour out the supernatant, and wash the precipitate with ethanol, acetone, and ether successively To clean, 60 ℃ constant temperature drying to constant weight.

[0027] The compound saponin is extracted by the following method: take 30 parts by weight of the medicinal materials Astragalus, 9 parts of Radix Notoginseng, and 12 parts of Salvia Miltiorrhiza, add 18 times the amount of water to soak for 1 hour, extract 3 times, and extract each time for 1 hour. Combine the two extracts, filter the extract with gauze and cotton, store in th...

Embodiment 3

[0030] The compound polysaccharide is extracted according to the following method: take 20 parts by weight of medicinal materials Astragalus, 5 parts of Radix Notoginseng, 15 parts of Salvia Miltiorrhiza, 12 parts of Angelica, and 5 parts of Chuanxiong, add 10 times the amount of water to soak for 24 hours, and extract once. Extract for 2 hours each time, filter, combine each filtrate, then concentrate to 0.6g crude drug / ml, then add absolute ethanol to 70% alcohol content, let it stand overnight, pour out the supernatant, and use it for precipitation Ethanol, acetone, and ether were washed successively until clean, and dried at a constant temperature of 60°C to constant weight.

[0031]Compound saponins are extracted according to the following method: take 20 parts by weight of medicinal materials Astragalus, 5 parts of Sanqi, 15 parts of Salvia, 12 parts of Angelica, and 5 parts of Chuanxiong, add 10 times the amount of water to soak for 24 hours, and extract once. Extract f...

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Abstract

The present invention relates to Chinese medicine for preventing and treating chronic renal lomerulus diseases, and is especially the medicine composition of one kind of compound Chinese medicine Tongmai oral liquid and its preparation process. The medicine composition is compounded with the effective parts of astragalus root, notoginseng, red sage and angelica, and contains compound polysaccharide and compound saponin in the ratio of 1-12. The medicine composition has the functions of benefiting Qi, promoting blood circulation, strengthening immunological stability, lowering the permeability of filtering membrane in renal lomerulus, improving microcirculation, etc., so that it can improve and stabilize kidney function.

Description

technical field [0001] The invention relates to the field of prevention and treatment of chronic glomerular diseases by traditional Chinese medicine, in particular to a pharmaceutical composition of the effective part of the traditional Chinese medicine compound Tongmai oral liquid for treating chronic nephritis and a preparation method thereof. Background technique [0002] Chronic glomerulonephritis is a common clinical disease and frequently-occurring disease. It is a group of immune diseases that originate in the glomerulus caused by various reasons. The clinical manifestations are similar, but the pathological changes are different, and the prognosis is not the same. Its clinical features are proteinuria, hematuria, edema, hypertension, and renal dysfunction. The condition is prone to relapse, and the renal function in the late stage of the disease will continue to deteriorate, and eventually it may develop into uremia, requiring expensive renal replacement therapy. Ac...

Claims

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Application Information

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IPC IPC(8): A61K36/53A61K9/08A61K9/10A61K9/16A61K9/20A61K9/48A61P13/12
Inventor 杨霓芝刘旭生林励黄兆胜林煌权钟丹赵代鑫赵玲包崑王立新刘明平
Owner NO 2 CLINICO MEDICINE COLLEGE GUANGZHOU UNIV OF TRADITIONAL CHINESE MEDICINE
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