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Fructus-sophorae Radix et Rhizoma sanguisorbae preparation and new preparing method

A technology of Burnet and preparations, applied in the preparation of Burnet sophorae and new preparations, which can solve the problems of many impurities, affecting clinical application, and large doses

Inactive Publication Date: 2006-10-25
FUKANGREN BIO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But in practice, because the medicine is prepared by powdering the medicinal materials into the medicine, there are many impurities and large doses, which seriously affect its clinical application.

Method used

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  • Fructus-sophorae Radix et Rhizoma sanguisorbae preparation and new preparing method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0064] The preparation method of dropping pill of the present invention:

[0065] prescription:

[0066] Sophora japonica (stir-fried) 132g Fructus aurantium (stir-fried) 66g Burnet (charcoal) 66g

[0067] Gardenia (stir-fried) 66g Rehmannia glutinosa 66g White peony (wine stir-fried) 66g

[0068] Nepeta 66g Toon skin (fried) 66g Scutellaria baicalensis 66g

[0069] PEG4000 100g

[0070] Makes 1000 pills

[0071] Preparation:

[0072] (1) Take Nepeta chinensis and Fructus aurantii medicinal materials, use steam distillation (or supercritical extraction method): chop the medicinal materials, and extract them according to the volatile oil extraction method in appendix XD of the 2005 Pharmacopoeia, until the height of the volatile oil does not increase any more ; The optimal process for β-CD inclusion of volatile oil is: the ratio of β-CD to water is 1∶8, the ratio of oil to β-CD is 1∶8, ultrasonication for 40 minutes, and the inclusion compound is obtained;

[0073] (2) Ta...

Embodiment 2

[0077] The preparation method of soft capsule of the present invention:

[0078] prescription:

[0079] Huaijiao (stir-fried) 400g Citrus aurantium (stir-fried) 200g Burnet (charcoal) 200g

[0080] Gardenia (stir-fried) 200g Rehmannia glutinosa 200g White peony (wine stir-fried) 200g

[0081] Nepeta 200g Toon skin (fried) 200g Scutellaria baicalensis 200g

[0082] PEG400 300g

[0083] Makes 1000 capsules

[0084] Preparation:

[0085] (1) Take Nepeta chinensis and Fructus aurantii medicinal materials, use steam distillation (or supercritical extraction method): chop the medicinal materials, and extract them according to the volatile oil extraction method in appendix XD of the 2005 Pharmacopoeia, until the height of the volatile oil does not increase any more ; The optimal process for β-CD inclusion of volatile oil is: the ratio of β-CD to water is 1∶8, the ratio of oil to β-CD is 1∶8, ultrasonication for 40 minutes, and the inclusion compound is obtained;

[0086] (2) Ta...

Embodiment 3

[0090] The preparation method of granule of the present invention:

[0091] prescription:

[0092] Huaijiao (stir-fried) 300g Citrus aurantium (stir-fried) 150g Burnet (charcoal) 150g

[0093] Gardenia (stir-fried) 150g Rehmannia glutinosa 150g White peony (wine stir-fried) 150g

[0094] Nepeta 150g Toon skin (fried) 150g Scutellaria baicalensis 150g

[0095] Made into 1000g

[0096] Preparation:

[0097] (1) Take Nepeta chinensis and Fructus aurantii medicinal materials, use steam distillation (or supercritical extraction method): chop the medicinal materials, and extract them according to the volatile oil extraction method in appendix XD of the 2005 Pharmacopoeia, until the height of the volatile oil does not increase any more ; The optimal process for β-CD inclusion of volatile oil is: the ratio of β-CD to water is 1∶8, the ratio of oil to β-CD is 1∶8, ultrasonication for 40 minutes, and the inclusion compound is obtained;

[0098] (2) Take Scutellaria baicalensis, Bur...

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Abstract

The present invention relates to a Chinese medicine composition for curing hematochezia, large-intestinal heat-accumulating and hemorrhoid swelling pain. It can be made into dripping pills and soft capsule preparation.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine composition and a preparation process thereof, in particular to a prescription for blood in the stool, accumulated heat in the large intestine, swelling and pain of hemorrhoids and a preparation process thereof. Background technique: [0002] Blood in the stool, heat accumulation in the large intestine, and swelling and pain of hemorrhoids are common clinical symptoms. Traditional Chinese medicine often adopts the methods of clearing away heat and stopping bleeding, reducing swelling and relieving pain, and the curative effect is remarkable. Huaijiao Diyu Pill is its representative drug. However, in practice, because the medicine is prepared by powdering the medicinal materials, it leads to many impurities and large doses, which seriously affects its clinical application. [0003] Compared with ordinary pills, the preparation prepared by the extraction process of the present invention can better...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61K9/06A61K9/14A61K9/16A61K9/20A61K9/48A61P9/14
Inventor 刘露
Owner FUKANGREN BIO PHARMA
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