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Compound forming agent with zedoary turmeric oil and method for preparing the same

A technology of zedoary oil and foaming agent, which is applied in the field of compound zedoary oil foaming agent and its preparation, and can solve problems such as foreign body sensation, cross-infection, uneven drug dispersion, etc.

Inactive Publication Date: 2006-09-06
郑起平 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, suppositories belong to the same dosage form, and there are some problems in specific use. The suppository has a process of softening and dissolving in the vagina, and the drug effect is slow, and the drug is dispersed unevenly and the spreading surface is narrow; Contaminate the medicine, and may cause cross-infection; in addition, if the suppository is used, the patient will feel a foreign body sensation in the body, which will bring discomfort to the patient

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Example 1: Econazole nitrate and zedoary oil were used as main ingredients, and Span-80, glycerin, Tween-80, sodium lauryl sulfate, etc. were used as emulsifiers. Mix 168g of zedoary oil with Span-80, glycerin, Tween-80, and sodium lauryl sulfate and mix evenly; mix 40g of nitroconazole with an appropriate amount of ethanol to dissolve; mix the two liquids and stir evenly, and then add Stir the distilled water evenly; pour it into a hand-pressed net type foam emulsion generating device, and generate foam by hand pressing a foam emulsion pump of the device; or pour it into a pressure-resistant container and add propellant, and then press the valve to pass the propellant to generate foam , that is.

Embodiment 2

[0022] Example 2: Econazole nitrate and zedoary oil were used as main ingredients, and Span-80, glycerin, Tween-80, sodium lauryl sulfate, etc. were used as emulsifiers. Take 190g of turmeric oil, Span-80, glycerin, Tween-80, and sodium lauryl sulfate, mix and stir evenly; mix 45g of nitroconazole with an appropriate amount of ethanol to dissolve; mix the two liquids and stir evenly, and then add Stir the distilled water evenly; pour it into a hand-pressed net type foam emulsion generating device, and generate foam by hand pressing a foam emulsion pump of the device; or pour it into a pressure-resistant container and add propellant, and then press the valve to pass the propellant to generate foam , that is.

Embodiment 3

[0023] Example 3: Econazole nitrate and zedoary oil are the main ingredients, and Span-80, glycerin, Tween-80, sodium lauryl sulfate, etc. are used as emulsifiers. Mix and stir zedoary oil 210g with Span-80, glycerin, Yewen-80 and sodium lauryl sulfate; mix 50g of nitroconazole with an appropriate amount of ethanol to dissolve; mix the two liquids and stir evenly, then add Stir the distilled water evenly; pour it into a hand-pressed net type foam emulsion generating device, and generate foam by hand pressing a foam emulsion pump of the device; or pour it into a pressure-resistant container and add propellant, and then press the valve to pass the propellant to generate foam , that is.

[0024] How to use: Before using this product, take a spare cannula (the cannula is for one-time use, replace one for each use) and put it outside the catheter. After the medicine bottle is fully shaken, gently insert the catheter with the cannula into the vagina In the cavity, press the pressur...

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PUM

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Abstract

Disclosed is a compound forming agent with zedoary turmeric oil and method for preparation, which consists of mixing oil of aromatic turmeric, Span-80, glycerin, Tween-80 and sodium dodecylsulfate, stirring homogeneously, mixing Xiaoyikangcuo with right amount of ethanol and dissolving, mixing the two obtained solutions, stirring homogeneously, charging distilled water and mixing homogeneously, making foams through a hand net type foam emulsion generation device.

Description

technical field [0001] The invention relates to a foaming agent and a manufacturing process thereof, in particular to a compound curcuma oil foaming agent and a preparation method thereof. Background technique [0002] Foam, as a pharmaceutical dosage form, has been recorded in Chinese Pharmacopoeia and Ministry Standards. Foam is usually extracted from raw materials or traditional Chinese medicines and prepared with appropriate amount of excipients to prepare liquid medicine, and then added to the pressure vessel and filled with propellant. become. [0003] Gynecological inflammation is a common and frequently-occurring disease. At present, suppositories are the most effective and convenient drug dosage form for treating this type of disease. However, suppositories belong to the same dosage form, and there are some problems in specific use. The suppository has a process of softening and dissolving in the vagina, and the drug effect is slow, and the drug is dispersed uneven...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/00A61P15/00A61P15/02B65D83/14A61K31/4164
Inventor 郑起平吕武清
Owner 郑起平
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