Saussurea and coptis preparation and preparation method
A technology of preparation and traditional Chinese medicine preparation, which is applied in the direction of pill delivery, medical formula, and resistance to vector-borne diseases, etc. It can solve the problems of many impurities, affecting clinical application, and large doses.
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Embodiment 1
[0062] The preparation method of dropping pill of the present invention:
[0063] prescription:
[0064] Coptis chinensis (made by Evodia rutaecarpa) 480g Woody fragrance 120g
[0065] PEG4000 100g
[0066] Makes 1000 pills
[0067] Preparation:
[0068] (1) Get the woody medicinal material and use steam distillation (or supercritical extraction method): chop the medicinal material and extract it according to the 2005 Pharmacopoeia Part I Appendix XD volatile oil extraction method until the height of the volatile oil does not increase any more; β- For CD inclusion, the best process is: the ratio of β-CD to water is 1:8, the ratio of oil to β-CD is 1:8, sonication for 30-70 minutes to obtain the inclusion compound; the obtained water extract is filtered and concentrated into a thick Extract, spare;
[0069] (2) Take Coptis rhizome powder, extract it twice with 1% (v / v) sulfuric acid cold soaking, 24 hours each time, filter, add calcium hydroxide fine powder to the filtrate...
Embodiment 2
[0072] The preparation method of soft capsule of the present invention:
[0073] prescription:
[0074] Coptis chinensis (made by Evodia rutaecarpa) 2400g Woody fragrance 600g
[0075] PEG400500g
[0076] Makes 1000 capsules
[0077] Preparation:
[0078] (1) Get the woody medicinal material and use steam distillation (or supercritical extraction method): chop the medicinal material and extract it according to the 2005 Pharmacopoeia Part I Appendix XD volatile oil extraction method until the height of the volatile oil does not increase any more; β- For CD inclusion, the best process is: the ratio of β-CD to water is 1:8, the ratio of oil to β-CD is 1:8, sonication for 30-70 minutes to obtain the inclusion compound; the obtained water extract is filtered and concentrated into a thick Extract, spare;
[0079] (2) Take Coptis rhizome powder, extract it twice with 1% (v / v) sulfuric acid cold soaking, 24 hours each time, filter, add calcium hydroxide fine powder to the filtrat...
Embodiment 3
[0082] The preparation method of granule of the present invention:
[0083] prescription:
[0084] Coptis chinensis (made by Evodia rutaecarpa) 2000g Woody fragrance 500g
[0085] Made into 1000g
[0086] Preparation:
[0087] (1) get the woody medicinal material and grind it into medicine;
[0088] (2) Take Coptidis medicinal material, percolate with 0.1% hydrochloric acid ethanol (95%) solution, collect the acidic ethanol extract, recover ethanol under reduced pressure, and obtain the concentrate;
[0089] (3) Combine the above active ingredients, add 5.0 g of aspartame and 260.0 g of dextrin, granulate, dry, and spray 5.0 g of essence to obtain 1000 g of granules.
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