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Fenugreek seed extract and its preparing process and application

A technology of extract and fenugreek, applied in the field of fenugreek extract and preparation thereof, can solve the problems of patients with side effects, high price and the like, and achieve the effects of clear biological activity, low cost and small dose

Inactive Publication Date: 2006-02-15
JILIN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although some methods have been used for treatment, many patients still have progressive development of kidney disease. At present, angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers are commonly used in my country to protect diabetic kidneys, but they are only effective in some patients. , and its price is expensive, side effects occur in some patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Preparation of fenugreek extract of the present invention

[0028] Weigh X grams of fenugreek, add about 5X grams of water, heat to boil, keep boiling slightly for 70 minutes, separate the decoction, add about 4X grams of water to the part of fenugreek, heat to boil, keep boiling slightly for 50 minutes, Combine two water decoctions; filter the water decoction, add ethanol to it to make the alcohol concentration reach 25%, cool to precipitate the precipitate; centrifuge, and discard the supernatant. The precipitate was washed three times with 25% ethanol, centrifuged, and the supernatant was discarded. The precipitate was distilled under reduced pressure to remove ethanol and dried under reduced pressure to obtain the fenugreek extract.

[0029] The resulting fenugreek extract was characterized as follows:

[0030] 1. Content Determination of Fenugreek Polysaccharides in Fenugreek Extract

[0031] Adopt sulfuric acid phenol method, concrete operation is as follows: ...

Embodiment 2

[0048] Proportion and preparation of granule containing fenugreek extract

[0049] Take 2000ml of aqueous solution containing 20% ​​fenugreek extract, add 16g of stevioside, after being completely dissolved and mixed, spray dry, dry the extract into extract powder, add 84g of dextrin to make granules, which contain 66.7% of fenugreek Luba extract. Made into 200 bags, each containing 1.5g. It can be administered to patients as medicine or health food. Take orally, 3 times a day, 1 bag each time, add water and stir to dissolve when taking.

Embodiment 3

[0051] Composition and preparation of capsules containing fenugreek extract

[0052] Crush 100g of fenugreek extract into fine powder, granulate, and pack into capsules; 30-50g of lactose or dextrin can also be added, granulated, and packed into capsules. The loading capacity is 0.35~0.40g; it can be administered to patients as medicine or health food. Take orally, 3 times a day, 3-4 capsules each time.

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PUM

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Abstract

The invention relates to an extract of fenugreek seeds, its preparing process and use thereof, wherein the extract contains 60-80 wt% of polysaccharides. Its preparing process comprises, making water boiled liquid of fenugreek seeds through grilling, charging ethanol for deposition and separation, discarding supernatant fluid through centrifugation, removing ethanol from the precipitate with vacuum distillation method, finally drying to obtain the extract of fenugreek seeds, which can be used for preparing the medicament for treating diabetes and diabetic nephropathy.

Description

technical field [0001] The present invention relates to a fenugreek extract extracted from fenugreek and a preparation method thereof; a drug crude compound with the extract as a bioactive component, and their application in medicines for treating diabetes and diabetic nephropathy; The extract is used in the preparation of health food with functions of regulating blood sugar, regulating and protecting kidney function and structure. Background technique [0002] Diabetes has become an important common and frequently-occurring disease in my country. With the obvious increase in the incidence of diabetes, the incidence of chronic complications of diabetes is quite prominent. Diabetic nephropathy is a common chronic complication of diabetes. Its incidence rate is 30-40% and 15-20% in type 1 and type 2 diabetes, respectively. It has become the main cause of threatening the life and health of diabetic patients. Diabetic nephropathy will cause serious damage to kidney function an...

Claims

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Application Information

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IPC IPC(8): A61K36/48A61P3/10A23L1/30A23L33/105
Inventor 卜凤泉李才刘忠英石艳苗春生张静
Owner JILIN UNIV
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