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Grosvenor's momordica fruit drip pill an dits preparation method

A technology of Luo Han Guo and fruit dripping pills, which is applied in pill delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc. It can solve the problems of low dissolution rate, inconvenient taking or carrying, and low drug content, so as to achieve dissolution and absorption Accelerated, improved bioavailability, highly automated results

Inactive Publication Date: 2005-10-26
北京博智绿洲医药科技有限公司
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AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
However, syrup oral preparations also have disadvantages such as low drug content, difficulty in taking and measuring accurately, inconvenient taking or carrying, etc.
[0008] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

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Embodiment Construction

[0033] Now with several groups of specific examples, the preparation method of Luo Han Guo dripping pills of the present invention will be further described.

[0034] [Group 1: Trials with a single substrate]

[0035] 1. Preparation of medicinal extracts: According to [Preparation Method 1], the dry extract powder containing active ingredients of 7 traditional Chinese medicines such as Luo Han Guo, Loquat Leaf, Morus Alba Cortex, Baiqian, Baibu, Campanulaceae, and Peppermint Oil was prepared for use;

[0036] 2. Substrate: polyethylene glycol 1000 , polyethylene glycol 4000 , polyethylene glycol 6000 , polyethylene glycol 10000 , polyethylene glycol 20000 , Span 40, polyoxyl 40 stearate, poloxamer, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac;

[0037] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0038] 4. Prepare according to the process given in [Preparation Method] 4-7, and you can get Luo Han...

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Abstract

A Chinese medicine in the form of dripping pill for treating cold, cough and bronchitis is prepared from 7 Chinese-medicinal materials including Grosvenor momordica fruit, loquat leaf, mulberry bark, mint oil, etc. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a pharmaceutical composition which has the effect of eliminating phlegm and relieving cough, and is commonly used in the treatment of diseases such as cold, cough and bronchitis, and particularly relates to a medicinal composition containing Luo Han Guo, loquat leaf, Morus alba, Baiqian, Baibu, Platycodon grandiflorum, peppermint oil, etc. An oral preparation of a pharmaceutical composition prepared from active ingredient extracts of seven traditional Chinese medicines as raw materials. Background technique [0002] According to the ministerial drug standard WS 3 -The compound Luo Han Guo oral liquid prepared by the preparation method given in B-3882-98 is a syrup oral preparation that has the effect of eliminating phlegm and relieving cough, and is often used for the treatment of colds, coughs, bronchitis and other diseases. It has been clinically verified. The curative effect is definite, and it is a commonly used medicine f...

Claims

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Application Information

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Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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