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Oil or fat composition

A kind of oil composition and composition technology, applied in the direction of pharmaceutical combination, inorganic/element cleaning composition, edible oil/fat, etc., can solve the problems of processability, flavor, and insufficient technology

Inactive Publication Date: 2005-09-28
KAO CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the current situation is that there are problems in terms of processability and flavor, and sufficient technology has not yet been established.

Method used

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  • Oil or fat composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Embodiment 1 Manufacture of oil composition

[0040] The following oil and fat compositions were produced. The composition of the obtained oil composition is shown in Table 1. Glyceride composition was determined by HPLC method, wherein the column used "TSKgelG2500H" manufactured by Tosoh Co., Ltd., THF was used as the elution solvent, the solvent flow rate was set to 0.4mL / min, and the detector was RI. The composition of fatty acids was determined by GLC method after methyl esterification (Japan Oil Chemistry Association "Standard Oil Analysis Test Method" 2.4.1.2-1996, 2.4.2.2-1996).

[0041] Fat composition 1 (product of the present invention)

[0042] Add 422.9g of 2,2-dimethyl-1,3-dioxolane-4-methanol and 0.64g of sodium hydroxide into a four-neck flask, dehydrate and alcoholize under reduced pressure at 80°C, and then cool to 50°C . Further, 355.3 g of high DHA content oil "DHA-22" (manufactured by MARUHA Co., Ltd.) was added thereto, and after reacting for 1....

Embodiment 2

[0051] Example 2 PPARγ activation test

[0052] The small intestinal epithelial cell line IEC-6 was spread on a 12-well plate and cultured in DMEM (5% FCS) for one day. Here, using a transfection reagent (Superfect transfection reagent; QIAGEN), at the amount of 0.5 μg / well each, the chimeric molecules expressing the GAL4-DNA-binding fragment (DBD) and the PPARγ coordination-binding fragment (LBD) were simultaneously The plastid (pGAL4-PPARγ-LBD) and the marker plastid (pREP) containing the GAL4 binding sequence upstream of the firefly luciferase gene were introduced. In order to improve the transfection efficiency, at the same time, the luciferase gene of the sea shiitake was programmed into pGAL4-PPARγ-LBD. Then, the culture solution was replaced with the DMEM (+250 μM BSA) medium containing the test substance (500 μM), and the culture was continued for 24 hours. After washing with PBS, the cells were lysed using the Dual Luciferase Assay System (Promega). Add the matrix ...

Embodiment 3

[0055] Example 3 Gelation evaluation

[0056] Each oil and fat: water=70:30 (weight / weight), gelation property was observed visually, and it evaluated by the following evaluation criteria. The results are shown in Table 1.

[0057] A: No fluidity, gelation.

[0058] B: Almost no fluidity, slightly gelled.

[0059] C: Fluid and partially gelled.

[0060] D: Fluidity, no gelation at all.

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Abstract

The present invention relates to an oil or fat composition containing the following components (A) and (B): (A) from 80 to 99.9 wt.% of a monoglyceride comprising 20 to 75 wt.% of docosahexaenoic acid (DHA) and 0.1 to 25 wt.% of icosapentaenoic acid (IPA), as the constituent fatty acids thereof, wherein the weight ratio of DHA / IPA being 2 or more; and (B) from 0.1 to 20 wt.% of a diglyceride. The oil or fat compositions according to the present invention are excellent in processability, have a good flavor, and are excellent in PPAR activating effects and beta oxidation activating effects so that they are beneficial as foods and animal feeds as well as pharmaceuticals for diabetes, hyperlipidemia and obesity.

Description

technical field [0001] The present invention relates to a Peroxisome Proliferator Activated Receptor (Peroxisome Proliferator Activated Receptor) having a specific glyceride composition and a fatty acid composition, good flavor, remarkable gelatinization and water absorption, excellent processability, and excellent It is an effective oil and fat composition for food, medicine, feed, etc. for PPAR) activation and β-oxidation activation. Background technique [0002] In recent years, people have paid more and more attention to the prevention and treatment of health care and diseases, and many studies have been carried out on eicosapentaenoic acid (C20:5, hereinafter referred to as IPA) and docosahexaenoic acid (C22:5) in fish oil or its components. 6, hereinafter referred to as DHA) and health-related functional research. Specifically, there are anti-arteriosclerosis effect, brain function-improving effect, visual function-improving effect, antitumor effect, anti-inflammation...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23D7/005A23D7/01A23D9/007A23D9/013A23K1/16A23K1/18A23L1/30A61K31/19A61K31/215A61K31/23A61K31/565A61P3/04A61P3/06A61P3/10A61P9/10A61P25/00A61P27/02A61P29/00A61P35/00C11B5/00C11C3/08
CPCA61K31/23A23K1/164A23V2002/00A61K31/565A23D7/0056A23L1/3004A61K31/19A23L1/3008A61K31/215A23D9/007A23K20/158A23L33/11A23L33/12A61P3/04A61P3/06A61P3/10A61P9/10A61P25/00A61P27/02A61P29/00A61P35/00A61K2300/00A23V2250/192A23V2250/182A23V2250/2136C11C3/10C11D3/08
Inventor 小池真村瀨孝利新居贤纪田中俊伯
Owner KAO CORP
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