Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Biological active nano titanium oxide ceramic for hard tissue repairing and its preparing method

A nano-titanium oxide and bioactive technology, which is applied in the field of bioactive materials and its preparation, can solve the problems of restricting the use of low- and middle-income patients, high cost of bioactive glass, and high cost, so as to reduce economic burden, be easy to realize, The effect of easy operation

Inactive Publication Date: 2004-12-15
SICHUAN UNIV
View PDF0 Cites 6 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The main problems that bioactive materials for hard tissue repair are facing are: first, the particles produced by degradation or wear of bioactive materials after implantation in the body may cause infection at the implantation site; The cost is high, among which the market price of hydroxyapatite is at least 5,000 RMB / kg, and the cost of bioactive glass and bioactive metal is higher, thus limiting the use of low- and middle-income patients

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Biological active nano titanium oxide ceramic for hard tissue repairing and its preparing method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] The present invention uses crystal redite nano-titanium oxide powder as a raw material, adds 2.5% by mass percentage of magnesium oxide powder as a grain growth inhibitor, uses pure alcohol as a solvent, and immerses crystal redite nano-titanium oxide powder and magnesium oxide powder in In alcohol, use an ultrasonic generator to fully mix the above powder for 10 minutes under the action of ultrasonic waves, dry it at room temperature, and use a cold isostatic press to shape the mixed powder at 50Mpa (MPa), and then put The shaped green body is put into a horse-bellied furnace, and is raised to the holding temperature at a heating rate of 10°C / min, and the holding temperature is 1000°C. After being kept at the heat preservation temperature for 2 hours, and then cooled to room temperature with the furnace, the biologically active nano titanium oxide ceramics with nano crystallization can be obtained.

Embodiment 2

[0018] Use anatase nano-titanium oxide powder as raw material, add 5% alumina powder as a grain growth inhibitor, and use analytical pure alcohol as a solvent to submerge the above-mentioned anatase nano-titanium oxide powder and alumina powder In alcohol, use an ultrasonic generator to fully mix the above powder for 20 minutes under the action of ultrasonic waves, dry it at room temperature, and use a cold isostatic press to shape the mixed powder under a pressure of 150 MPa (MPa). Then put the molded green body into the horse-bellied furnace, and rise to the holding temperature at a heating rate of 50°C / min, and the holding temperature is 600°C at this time. After being kept at the heat preservation temperature for 5 hours, and then cooled to room temperature with the furnace, the biologically active nano titanium oxide ceramics with nano crystallization can be obtained.

Embodiment 3

[0020] Use the mixed nano-titanium oxide powder of anatase powder and crystal red stone powder as raw material, add calcium pyrophosphate powder with a mass percentage of 1% as a grain growth inhibitor, and use analytical pure alcohol as a solvent to submerge the above two mixed powders In alcohol, use an ultrasonic generator to fully mix the mixed powder for 30 minutes under the action of ultrasonic waves, and then dry it at room temperature. Put the green body into the horse-bellied furnace, and rise to the holding temperature at a heating rate of 10°C / min. At this time, the holding temperature is 1200°C. After being kept at the heat preservation temperature for 3 hours, and then cooled to room temperature with the furnace, the biologically active nano-crystallized nano-titanium oxide ceramics can be obtained.

[0021] The size of the nanocrystalline grains 1 in the bioactive nano-titanium oxide ceramics obtained in the present invention is between 0.1 and 1 micron, and ther...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
particle diameteraaaaaaaaaa
sizeaaaaaaaaaa
sizeaaaaaaaaaa
Login to View More

Abstract

The bioactive nano titania ceramic block is prepared with nano titania powder meeting biological and medical requirement, such as rutile powder and / or anatase powder, as main material, and through mixing with magnesium oxide powder, alumina powder, calcium pyrophosphate or other crystal growth inhibitor, cold isostatic pressing formation, and sintering. Under intracorporal physiological environment condition, the ceramic block can adsorb calcium and phosphorus ion to form surface bone apatite layer for bioactive chemical combination with bone tissue. The bioactive nano titania ceramic may be implanted into tooth or other bone fault cavity to form bioactive combination safely and reliably in relatively low cost.

Description

1. Technical field [0001] The invention relates to bioactive materials used for hard tissue repair in biomedical engineering and its preparation technology, in particular to bioactive nano-titanium oxide ceramics used for hard tissue repair and its preparation method. 2. Background technology [0002] Bioactive materials for hard tissue repair refer to materials that chemically combine with bone tissue through the formation of a bone-like apatite interface layer after implantation. Before the present invention was made, bioactive materials widely used in human hard tissue repair included hydroxyapatite ceramics, bioactive glass, surface-modified bioactive metals, and the like. These materials are implanted into the bone, and the chemical combination of bioactivity is realized by forming a bone-like apatite interface layer on the interface between the implanted bioactive material and the bone tissue. The main problems that bioactive materials for hard tissue repair are facin...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C04B35/46
Inventor 杨帮成虞奇峰吴尧张兴栋
Owner SICHUAN UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com