Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Troxerutin for injection and method for preparing the same

A technology for injection and water for injection, which is applied in the field of troxerutin for injection and its preparation, which can solve the problems of inconvenient transportation of large-capacity infusion, unstable quality of injection, and low bioavailability, so as to improve bioavailability , easy storage and transportation, good water solubility

Inactive Publication Date: 2004-09-01
崔彬
View PDF0 Cites 8 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its solid preparation has low bioavailability, the quality of the injection is not stable enough, and the transportation of large-capacity infusion is inconvenient, and the shelf life is short

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0007] Embodiment 1: it is 400 grams of raw material hydroxyethyl rutin (injection grade) aseptic powder, is equipped with water for injection to 10000ml, according to prior art, it is made into freeze-dried powder injection. In this formulation, an appropriate amount of mannitol can be added as an excipient.

Embodiment 2

[0008] Embodiment 2: it is 400 grams of raw material hydroxyethyl rutin (injection grade) aseptic powder, is equipped with water for injection to 10000ml, filters, sterilizes, dries (or does not dry), and is made into nanopowder according to the nanotechnology method injection.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

Troxerutin for injection and method for preparation, wherein troxerutin (injection level) powder as a medicinal raw material is dissolved in a definite quantity of water for injection to obtain sterility solution, the freeze dried injection is finally prepared through cryodesiccation, or the prepared sterility solution can be condensed, dried (or not) to obtain the freeze dried injection through nano techniques.

Description

Technical field: [0001] The invention relates to troxerutin for injection and a preparation method thereof, and belongs to the technical field of medicines and preparation methods thereof. Background technique: [0002] Cardiovascular and cerebrovascular diseases are diseases with high incidence and great threat to human life. Troxerutin (other names include hydroxyethyl rutin, Weinaolutong, vitamin P 4 ), can inhibit platelet aggregation, prevent thrombosis, and at the same time resist vascular damage caused by 5-hydroxytryptamine and bradykinin, increase capillary resistance, reduce capillary permeability, and prevent vascular permeability Elevated edema. It has a significant protective effect on acute ischemic brain injury. It is suitable for hemiplegia, aphasia, pre-myocardial infarction syndrome, arteriosclerosis and other diseases caused by cerebral thrombosis and cerebral infarction. At present, commercially available troxerutin preparations include tablets, capsu...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/14A61K9/19A61K31/352A61P7/02A61P9/10
Inventor 崔彬
Owner 崔彬
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com