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Interverterbral fusion implement

An intervertebral fusion cage and polygon technology, which is applied in the field of medical materials, can solve the problems of foreign body reaction and low incidence of complications, and achieve the effects of no foreign body reaction, excellent curative effect and high fusion rate.

Inactive Publication Date: 2003-08-20
成都迪康中科生物医学材料有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0007] Finding an alternative with an elastic modulus close to that of human bone and a low incidence of complications after implantation into the human body has become the focus of current research. Polymer materials have attracted widespread attention from scholars. It has been reported that plastics such as nylon and polyether ether Ketone's cervical fusion device has improved biocompatibility with the human body, but the implant still exists in the human body for a long time, resulting in different degrees of foreign body reactions

Method used

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Examples

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Effect test

Embodiment 1

[0026] Example 1: Poly DL-lactic acid material with a molecular weight of 300,000 was molded by an injection machine at an injection temperature of 200° C. to make an intervertebral fusion device. The intervertebral fusion cage is a hollow cylinder with a quadrilateral or hexagonal cross-section. The side wall has a hole with a diameter of 2 mm. The finished product has been tested with a pressure resistance of 913 kg. The in vitro degradation test is shown in Table 1.

Embodiment 2

[0027] Example 2: The copolymer material of DL-lactide and L-lactide (30:70), with a molecular weight of 500,000, was molded by an injection machine to make an intervertebral cage, and the injection temperature was 175°C. The intervertebral fusion cage is a hollow cylinder with an octagonal cross-section and a hole in the side wall with a diameter of 4mm. The finished product has been tested with a pressure resistance of 958 kg. The in vitro degradation test is shown in Table 1.

Embodiment 3

[0028] Example 3: The L-polylactic acid material, with a molecular weight of 400,000, was molded by an injection machine to make an intervertebral fusion cage. The injection temperature was 220°C. The cross-section was quadrilateral, and the side wall was open with a diameter of 1mm. The finished product was tested. , anti-pressure 985 kg, see Table 1 for in vitro degradation experiments.

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Abstract

The interverterbral fusion implement for cervical vertebra anterior operation is one hollow column with polygonal or circular cross section, holes on side wall and sharp teeth on the upper and the lower surfaces. It is made of polymer material capable of being absorbed by human body, poly(DL-lactic acid), poly(L-lactic acid), polyglycolic acid or their copolymer. It has determined early-stage locking effect, late-stage bone fusion effect, good biocompatibility and proper mechanical structure, and may be self-degraded after being fused with vertebra. It results in no rejection and may be also used in thoracic vertebra and lumbar vertebra operation.

Description

technical field [0001] The invention belongs to the field of medical materials, and more specifically relates to a medical operation implant, an intervertebral fusion device used in anterior cervical surgery. It is also suitable for lumbar spine and thoracic spine surgery. Background technique [0002] Since Robinson-Smith and Cloward pioneered anterior cervical decompression and fusion (ACDF) in the 1950s, it can effectively remove intervertebral discs, hypertrophic osteophytes, and fractures protruding to the front of the spinal canal. Fragments, and can be grafted and fused at the same time, it has been widely used in the treatment of cervical trauma, tumors, cervical spondylosis. In anterior cervical decompression and fusion, the bone graft method and bone graft material are still the focus of debate: the clinical satisfaction rate and bone graft fusion rate of multi-level fusion are far lower than those of single-level fusion. Secondary anterior or...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B17/70A61L27/14A61L27/58
Inventor 唐天驷钱帮平杨同其李开南李伟熊成东
Owner 成都迪康中科生物医学材料有限公司
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