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Sweet wormwood oil drop pills and preparation method thereof

A technology of Artemisia annua oil and oil dripping pills, which can be used in pill delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc. It can solve problems such as health effects and aging of the capsule skin, achieve small side effects and avoid gastrointestinal irritation Symptoms, effects of avoiding the first-pass effect

Inactive Publication Date: 2007-07-11
北京博智绿洲医药科技有限公司
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  • Abstract
  • Description
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  • Application Information

AI Technical Summary

Problems solved by technology

[0016] Gelatin is often used as the capsule body material for soft capsules. Due to the characteristics of gelatin and the preparation technology, the outer skin of the soft capsules is often prone to aging during the storage process, which will produce certain insoluble substances in the human body. Residues in the human body will also have a certain impact on the health of the human body. Therefore, many international and domestic medical workers are constantly conducting in-depth research in order to seek to improve this phenomenon.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0040] The preparation method of Artemisia annua oil dripping pills of the present invention will be further described with several groups of specific examples.

[0041] Group 1: Tests with a single matrix

[0042] 1. Raw materials containing active pharmaceutical ingredients: artemisia annua oil;

[0043] 2. Substrate: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. pharmaceutical carrier;

[0044] 3. Proportion: take g or kg as the unit, by weight parts, artemisia annua oil: substrate = 1:1~1:9;

[0045] 4. Then prepare according to the [preparation method], and various specifications of Artemisia annua oil dripping pills can be prepared.

[0046] [test results]

[0047] Test 1: In order to observe the difference in quality of Artemisia annua oil drop pills prepared when the ratio of Artemisia annu...

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PUM

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Abstract

The invention relates to a medicinal oral preparation of sweet wormwood oil drop pill, which has the functions of cough-relieving, phlegm reducing and treating chronic bronchitis, it has the advantages of high biological availability, quick-speed medicine release, quick-speed effect, less toxic and side effects, higher medicinal content, smaller amount of administration, accurate administration dosage, easy administering, low price, and facilitated carrying. The medicine is prepared through the conventional drop pill preparing process.

Description

technical field [0001] The present invention relates to a kind of medicine composition that has the functions of eliminating phlegm, relieving cough and relieving asthma, and is used for treating chronic bronchitis. Pill preparations. Background technique [0002] Artemisia annua oil soft capsule prepared according to the formula and extraction process given in the national drug standard WS-10934 (ZD-0934)-2002, is a kind of anti-phlegm, cough and anti-asthma effect, used for the treatment of chronic bronchial The oral preparation of phlegm has been clinically verified and has definite curative effect. It is a commonly used oral preparation for clinical and family treatment of chronic bronchitis. [0003] The following is the formula and extraction process given in the pharmaceutical standard WS-10934 (ZD-0934)-2002: [0004] Prescription: Artemisia annua oil 20g, refined edible vegetable oil 60g; [0005] Preparation method: Mix artemisia annua oil and refined edible veg...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/282A61P11/00A61K135/00
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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