Wound dressing for first aid
A first-aid dressing and trauma technology, applied in the field of medicine, can solve the problems of expensive human fibrinogen, limited application, solution wash-out, etc., and achieve the effect of controlling secondary infection, good safety, and easy operation
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Embodiment 1
[0034] The sheet-like PVA sponge is used as the substrate of the sheet;
[0035] Spray 10mg / ml gelatin solution on the base sheet with a large-hole sprayer, and air-dry at room temperature; the amount of gelatin can be determined according to the application occasion of the sheet. Typically, gelatin is flowable and dispersed in a phosphate solution to a final concentration of at least 2 mg / cm 2 , usually 1mg / cm 2 to 50mg / cm 2 , the most commonly used is 2mg / cm 2 to about 10mg / cm 2 .
[0036] Spray the calcium alginate solution onto the substrate and dry it by air drying;
[0037] Spray the covalently bound bovine thrombin solution with a concentration of 10 activity units / ml onto the substrate with a small-hole sprayer, and dry it in a vacuum oven for 2 hours to a final concentration of 2 activity units / cm 2 ;
[0038] Spray the 6-aminocaproic acid solution with a concentration of 10 mg / ml on the substrate with a fine small-hole sprayer, and the final concentration is 1...
Embodiment 2
[0047] The sheet-like PVA sponge is used as the substrate of the sheet, the calcium ion additive is calcium chloride, the animal thrombin is covalently bonded bovine thrombin, and the aminocaproic acid is 8-aminocaproic acid. First spray 15 mg / ml gelatin solution on the substrate, then spray calcium chloride solution, thrombin solution with a concentration of 10 activity units / ml and 8-aminocaproic acid solution with a concentration of 20 mg / ml.
[0048] Animal hemostatic test and effect are the same as in Example 1.
Embodiment 3
[0050] The sheet-like PVA sponge is used as the substrate of the sheet, the calcium ion additive is calcium alginate, the animal thrombin is covalently bonded bovine thrombin, and the aminocaproic acid is 6-aminocaproic acid. After the solution of the above materials is sprayed on the substrate, broad-spectrum antibiotics, morphine and fibroblast growth factor are sprayed. Animal hemostatic test and effect are the same as in Example 1.
[0051] The size and shape of the first-aid trauma patch of the present invention can be determined according to specific uses, and can be spherical, conical, cubic or cylindrical, so that it is used for special parts of the body, and square sheet is commonly used. The present invention can also adhere the above-mentioned calcium ion additive, animal thrombin and aminocaproic acid to the synthetic polymer or natural fiber bandage.
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