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Liquid dressing based on porphyridium and preparation method thereof

A technology of liquid dressing and cyanobacteria, which is applied in the fields of medical science and bandages, can solve the problems of complex composition, dependence on antibacterial effect, slow wound healing of non-natural components, etc., achieving simple preparation method, avoiding protruding scars, Excellent moisturizing effect

Pending Publication Date: 2022-03-25
浙江清荣生物科技发展有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the embodiments of the present invention is to provide a liquid dressing and its preparation method, which has the characteristics of natural and safe ingredients and comfortable skin feeling, and the preparation method of the liquid dressing is simple and low in cost, and is suitable for industrial application to solve related problems. The technology has complex components, antibacterial effect depends on the addition of non-natural components and slow wound healing

Method used

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  • Liquid dressing based on porphyridium and preparation method thereof
  • Liquid dressing based on porphyridium and preparation method thereof
  • Liquid dressing based on porphyridium and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] A liquid dressing, comprising the following components in parts by mass: 5 parts of glucosamine derivatives from Porphyridum sp., 0.2 parts of Porphyrococcus polysaccharide, 0.05 parts of Porphyrococcus phycobiliprotein, and the balance is deionized water. The quantity is 100 servings.

[0030] The preparation method is as follows:

[0031] (1) The steps of obtaining Porphyrococcus polysaccharides and water-soluble Porphyrococcus phycobiliprotein from Porphyrococcus algae fluid include centrifugation, water washing, ultrafiltration and other steps. Glucosamine derivatives (>60kDa) are prepared from Porphyridum algae raw materials. Chitosan is first obtained by degreasing algae mud after homogenization, acid / alkali washing and other steps, and then undergoes hydrolysis, ethanol precipitation, alcohol washing and vacuum rotary evaporation and other steps to obtain Porphyridium glucosamine.

[0032] (2) Add deionized water into the batching tank, then add 5 parts of gluc...

Embodiment 2

[0038] A liquid dressing, which contains the following components in parts by mass: 0.5 parts of glucosamine derivatives, 0.1 parts of Porphyridum polysaccharide, 0.01 part of Porphyridum phycobiliprotein, and the balance is deionized water, the total amount is 100 parts .

[0039] The preparation method is as follows:

[0040] (1) Separating and purifying the Porphylococcus algae liquid to obtain Porphyrococcus polysaccharides, water-soluble Porphyrococcus phycobiliproteins and glucosamine derivatives (>60kDa). This step is the same as that in Example 1 and will be briefly mentioned here.

[0041] (2) Add deionized water into the batching tank, then add 0.5 parts of glucosamine derivatives into the batching tank, stir at 30°C and 300 rpm for 20 minutes, and mix well;

[0042] (3) Add 0.01 part of Porphylococcus phycobiliprotein into the mixed solution obtained in (2), and continue to stir for 20 minutes until the solution is uniform;

[0043] (4) Slowly add 0.1 part of Porp...

Embodiment 3

[0047] A liquid dressing, comprising the following components in parts by mass: 10 parts of glucosamine derivatives, 1 part of Porphyridum polysaccharide, 0.1 part of Porphyridum phycobiliprotein, and the balance is deionized water, the total amount is 100 parts .

[0048] The preparation method is as follows:

[0049] (1) Separating and purifying the Porphylococcus algae liquid to obtain Porphyrococcus polysaccharides, water-soluble Porphyrococcus phycobiliproteins and glucosamine derivatives (>60kDa). This step is the same as that in Example 1 and will be briefly mentioned here.

[0050] (2) Add deionized water into the batching tank, then add 10 parts of glucosamine derivatives into the batching tank, stir at 30°C and 300rpm for 20 minutes, and mix well;

[0051] (3) Add 0.1 part of Porphylococcus phycobiliprotein into the mixed solution obtained in (2), and continue to stir for 20 minutes until the solution is uniform;

[0052] (4) Slowly add 1 part of Porphyridum polysa...

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Abstract

The invention belongs to the field of wound surface nursing, and particularly relates to a porphyridium-based liquid dressing and a preparation method thereof.The liquid dressing is prepared from, by mass, 0.5-10 parts of glucosamine derivatives, 0.1-1 part of porphyridium polysaccharide, 0.01-0.1 part of porphyridium phycobiliprotein and the balance deionized water, and the total amount is 100 parts. Wherein the porphyridium polysaccharide, the porphyridium phycobiliprotein and the glucosamine derivative are obtained by separating and purifying a porphyridium solution. The physicochemical property and safety of the liquid dressing accord with related standards, and the liquid dressing is proved to have antibacterial activity and wound healing promoting performance. The preparation method of the liquid dressing is simple, and the liquid dressing has the characteristics of natural and safe components, good film-forming property and comfortable skin feeling, and is suitable for industrial application.

Description

technical field [0001] The invention relates to the field of wound care, in particular to a liquid dressing and a preparation method thereof. Background technique [0002] The skin is the largest organ in the human body. It plays the role of organically isolating the human body from the external environment, regulating the body's water and electrolyte balance, resisting the invasion of foreign bodies, bacteria, viruses, etc., preventing mechanical damage, and resisting the harm of ultraviolet radiation to the human body. Superficial skin injuries including abrasions, scratches, scalds, and burns are more common. Traditional wound care products such as band-aids / gauze have disadvantages such as strong foreign body sensation, easy adhesion to the wound, easy to fall off after being wet, easy to infection, and long healing cycle resulting in obvious scars after healing. [0003] The theory of moist healing, which began in the 1960s, pointed out that a humid environment can inc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00
CPCA61L26/0023A61L26/0066A61L26/0061A61L26/0047A61L2300/404A61L2300/408A61L2300/45C08L5/00C08L89/00
Inventor 章真张荣庆张静刘晓军姚丽萍陈夏
Owner 浙江清荣生物科技发展有限公司
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