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Liquid dressing for promoting wound repair and preparation method thereof

A liquid dressing and wound repair technology, applied in medical science, bandages, etc., can solve the problem of not promoting wound healing, achieve good appearance and experience, good antibacterial effect, and promote the effect of proliferation and migration

Inactive Publication Date: 2022-03-11
铂生卓越生物科技(北京)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But the liquid band-aid of this invention does not add ingredients that can promote wound healing, and has no wound healing effect

Method used

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  • Liquid dressing for promoting wound repair and preparation method thereof
  • Liquid dressing for promoting wound repair and preparation method thereof
  • Liquid dressing for promoting wound repair and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Example 1: Preparation of Liquid Dressing Samples

[0040]1. Preparation of Liquid Dressing Sample 1

[0041] 1.1 Weigh each material according to the ratio in Table 1.

[0042] Table 1: Material Proportion

[0043]

[0044] 1.2 Preparation of liquid dressing

[0045] The concrete preparation process of this liquid dressing comprises:

[0046] Step 1): Dissolve water-soluble chitosan in purified water, let it stand for defoaming, add glycine and stir to dissolve, then add Poloxamer 188 and Poloxamer 407, and incubate overnight at 4°C to obtain a uniform and transparent mixture Liquid A;

[0047] Step 2): Exosomes were added to the mixed solution A, and stirred evenly, and the liquid dressing sample 1 for promoting wound repair was obtained after the preparation was completed.

[0048] 2. Preparation of Liquid Dressing Sample 2

[0049] 2.1 Weigh each material according to the ratio in Table 2.

[0050] Table 2: Material Proportion

[0051]

[0052] 2.2 P...

Embodiment 3

[0058] Embodiment 3: prepare chitosan reagent

[0059] Table 3: Material Proportion

[0060]

[0061] 3.2 Preparation of liquid dressings

[0062] Dissolve the water-soluble chitosan in purified water, let stand to defoam, add glycine and stir to dissolve, and then obtain liquid dressing sample 3.

Embodiment 2

[0063] The film-forming property of embodiment 2 liquid dressing sample

[0064] In order to investigate the film-forming performance of the liquid dressing prepared by the present invention, liquid dressing samples 1 to 3 were tested for film formation, and the specific method was as follows:

[0065] Apply an appropriate amount of liquid dressing sample on any area of ​​the skin, wait for a film to be formed, and observe the film-forming effect (see figure 1 ), and record the film-forming time at the same time, the results are shown in Table 4.

[0066] Table 4: Film formation time of liquid dressings with different compositions

[0067]

[0068] The results in Table 4 show that the film-forming time of liquid dressing sample 1 prepared by the present invention is shorter than that of liquid dressing sample 2, while liquid dressing sample 3 cannot form a film.

[0069] in addition, figure 1 The results show that the liquid dressing sample 1 and sample 2 prepared by the...

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Abstract

The invention provides a liquid dressing for promoting wound repair. The liquid dressing comprises an exosome, a film-forming agent and a hemostatic. The invention further discloses a preparation method of the liquid dressing for promoting wound repair. The liquid dressing prepared by the preparation method disclosed by the invention has relatively good hemostatic and antibacterial effects after wound surface film formation, and can effectively promote wound surface repair and accelerate wound healing.

Description

technical field [0001] The invention relates to the technical field of medical dressings, in particular to a liquid dressing for promoting wound repair and a preparation method thereof. Background technique [0002] In medicine, a dressing generally refers to a covering that temporarily covers a wound and has a protective effect. When the skin is injured, choose a suitable dressing to cover the wound, which is beneficial to control bleeding, prevent infection, and absorb secretions to promote rapid wound healing. Traditional medical dressings mainly use cotton gauze for care, which can keep the wound dry and breathable, and control infection. Although cheap and convenient to use, the pores of cotton products are not enough to prevent most microorganisms from entering the wound healing environment, and it is easy to prevent adhesion with the wound, causing pain and secondary trauma. Moreover, the air permeability is not ideal, and the water vapor and sweat normally secreted...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00
CPCA61L26/0057A61L26/0023A61L26/0019A61L26/0066A61L26/009A61L2300/404A61L2300/30A61L2300/412A61L2300/214A61L2300/418C08L5/08C08L71/02
Inventor 盛宏霞吉建飞高雪松李小刚陈晓颖李梁
Owner 铂生卓越生物科技(北京)有限公司
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