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Device and method for screening particles within fluid sample

A technology for fluid samples and fluids, applied in chemical instruments and methods, biochemical equipment and methods, enzymology/microbiology devices, etc., can solve problems such as low sorting efficiency and complicated process, and achieve fast sorting process , Small size, guaranteed purity effect

Pending Publication Date: 2021-12-03
SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0006] In view of this, the present invention provides a device and method for screening particles in a fluid sample to solve the problems of complicated process and low sorting efficiency in the existing marker sorting method

Method used

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  • Device and method for screening particles within fluid sample
  • Device and method for screening particles within fluid sample
  • Device and method for screening particles within fluid sample

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Embodiment Construction

[0031] In order to make the object, technical solution and advantages of the present invention clearer, the specific implementation manners of the present invention will be described in detail below in conjunction with the accompanying drawings. Examples of these preferred embodiments are illustrated in the accompanying drawings. The embodiments of the invention shown in and described with reference to the drawings are merely exemplary, and the invention is not limited to these embodiments.

[0032] Here, it should also be noted that, in order to avoid obscuring the present invention due to unnecessary details, only the structures and / or processing steps closely related to the solution according to the present invention are shown in the drawings, and the related Other details are not relevant to the invention.

[0033] Embodiments of the present invention firstly provide a device for screening particles in a fluid sample, such as figure 1 As shown, the shown device mainly in...

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Abstract

The invention discloses a device for screening particles within a fluid sample. The device comprises a substrate having a substrate surface; a fluid sample channel, wherein the fluid sample channel is attached to the substrate surface and extends along a first direction, at least one inlet for inputting the fluid sample is formed in a first end of the fluid sample channel, and at least two outlets for outputting the fluid sample are formed in a second end of the fluid sample channel; and a surface sound wave generator, wherein the surface sound wave generator is arranged on the substrate surface and used for generating a surface sound field which is transmitted in a direction perpendicular to the first direction and is applied to the fluid sample channel, and the surface sound field comprises a standing wave sound field and a traveling wave sound field which are sequentially distributed in the first direction. Based on the device, the invention further provides a method for screening the particles within the fluid sample. Different particles in the fluid sample are screened through combination of the standing wave sound field and the traveling wave sound field. According to the device and the method, particles in fluid samples such as cells can be effectively and rapidly screened.

Description

technical field [0001] The invention relates to the technical field of biological particle separation, in particular to a device and method for screening particles in a fluid sample. Background technique [0002] There are many kinds of cells in the living body, such as somatic cells, blood cells, lymphocytes, etc. It is of great significance for the sorting of cells of the same or different species. Taking cancer cells as an example, cancer-related surgery can remove the lesion better, but it cannot prevent cancer cells from spreading to the circulatory system. Tumor cells often spread throughout the body along with the circulatory system, resulting in a high recurrence rate of the resected tumor. Therefore, the detection of cells is particularly important. The metastasis of tumor cells can take root in other tissues and organs through the circulatory system, such as blood and lymph. If circulating tumor cells can be detected and obtained in the patient's blood sample, no...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/42C12M1/00B01L3/00
CPCC12M23/16C12M35/02C12M35/04B01L3/502761
Inventor 刘源挺孟龙乌玛·儒可周伟刘秀芳陈卫兴
Owner SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
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