Noninvasive blood glucose detection device and method based on MIC-PCA-NARX correction algorithm

Abstract

The invention relates to a noninvasive blood glucose detection device and method based on an MIC-PCA-NARX correction algorithm, and belongs to the technical field of biomedical signal acquisition and processing. The device comprises a signal conditioning circuit, a data storage module, a transmission module, a light source driving circuit, a constant temperature control module, a probe plate, an MCU, a power supply module and a display module. Four light sources and a photoelectric receiver are integrated on the probe plate; the MCU controls equipment operation according to information input by a user, transmits and stores data and a blood glucose value is calculated through the blood glucose prediction model based on the MIC-PCA-NARX correction algorithm, the stability and accuracy of blood glucose noninvasive detection are improved, and meanwhile the equipment cost is reduced.

Description

technical field [0001] The invention belongs to the technical field of biomedical signal acquisition and processing, and relates to a noninvasive blood sugar detection device and method based on a MIC-PCA-NARX correction algorithm. Background technique [0002] At present, automatic biochemical analyzer detection method and rapid blood glucose meter measurement method are mainly used to detect blood glucose concentration. Among them, the automatic biochemical instrument detection method collects blood samples by taking blood from a vein, then centrifuges the collected blood samples to obtain serum, and obtains the blood glucose concentration value of the subject through biochemical instrument analysis. The accuracy of the blood glucose concentration measured by the automatic biochemical instrument detection method is relatively high, but due to the large demand for blood samples, the long detection time, and the large volume of biochemical instruments used for detection, it ...

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Problems solved by technology

[0006] At present, the existing non-invasive blood glucose meters in China are mainly designed based on the principle of heat metabolism method, such as the non-invasive blood glucose meter developed by Bobang Fangzhou. Although the detection value of this instrument is relatively good in high blood sugar areas, it cannot be used as a guide for clinical medication at present.

[0007] In recent years, there have been more and more researchers at home and abroad researching and developing non-invasive detection of blood glucose. However, as far as the current domestic situation is concerned, the blood glucose equipment based on near-infrared light does not eliminate the temperature factor, but only considers the influence of temperature in the algorithm. However, the absorbance of near-infrared light by temperature is a complex nonlinear effect, and the algorithm cannot remove the temperature effect very well. In addition, mature and reliable non-invasive blood glucose devices are still scarce, and foreign non-invasive blood glucose devices are expensive to purchase and still lack maturity. , the penetration rate in the country is extremely low

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