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DNA hybridization information storage encryption method based on probe blocking and unblocking

An encryption method and information storage technology, which is applied in the field of DNA hybridization information storage encryption based on probe sealing and unblocking, can solve the problems of low information security, DNA hybridization storage technology has not yet realized the encryption function, etc., and achieve the goal of improving security Effect

Active Publication Date: 2021-10-22
HUNAN UNIV OF SCI & TECH
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] In order to solve the defects and deficiencies in the current technology, the purpose of the present invention is to provide a DNA hybridization information storage encryption method based on probe blocking and unblocking, to solve the problem that the existing DNA hybridization storage technology has not yet realized the encryption function and the information security is low. technical issues

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  • DNA hybridization information storage encryption method based on probe blocking and unblocking
  • DNA hybridization information storage encryption method based on probe blocking and unblocking
  • DNA hybridization information storage encryption method based on probe blocking and unblocking

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Embodiment 1

[0044] Specifically, the embodiment of the present invention provides a method for storing and encrypting DNA hybridization information based on probe blocking and unblocking. The following will take the writing target information "encryption" (two Chinese characters) as an example to describe the method for storing and encrypting DNA information of the present invention. Further detailed description, including the following steps:

[0045] Such as figure 2 As shown, the parallel addressing and writing method for DNA information storage in this embodiment includes:

[0046] 1) Convert the target information, that is, the two Chinese characters "encryption" into binary code, 10111100110100111100001111011100 and divide it into 8 fields, each field corresponds to a data unit, including 4 binary digits;

[0047] 2) Map the 1 / 0 value on the 4 binary digits of each of the above fields to the presence / absence combination of the 4 DNA coding strands B1, B2, B3, and B4; for example, ...

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Abstract

The invention discloses a DNA hybridization information storage encryption method based on probe blocking and unblocking, and belongs to the technical field of DNA storage. The DNA hybridization information storage encryption method based on probe blocking and unblocking comprises a set of DNA oligonucleotide probe combination with a fluorophore, a quenching group and restriction enzyme recognition sites and a set of restriction enzyme combination, wherein the specific restriction enzyme can cut off a quenching group of the specific probe, so the probe is activated; in the DNA hybridization process of DNA hybridization storage information reading, if a probe which is not correctly activated is directly used, due to the existence of a quenching group, an effective fluorescence detection signal cannot be obtained after hybridization, and the storage information cannot be read. Hard encryption of the DNA hybridization information storage technology is achieved, the safety of the DNA hybridization information storage technology can be effectively improved, and application of the technology in the fields of military, government affairs and commercial encryption storage is promoted.

Description

technical field [0001] The invention belongs to the technical field of DNA storage, in particular to a method for storing and encrypting DNA hybridization information based on probe blocking and unblocking. Background technique [0002] DNA storage technology is the crystallization of the cross fusion of life science and information science. DNA is the genetic material selected in the long process of biological evolution. As an information storage material, DNA has the characteristics of extremely long storage time, large storage information capacity, and strong environmental adaptability, and has great development potential. At present, the mainstream technology in the field of DNA storage is based on DNA synthesis and sequencing. Although this technology has high information density, it has weaknesses such as poor parallelism, long read and write time, and low encryption performance, which limits the practical application of DNA storage technology. To this end, the applic...

Claims

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Application Information

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IPC IPC(8): G16B25/00G06F21/60G16B30/00G16B50/00
CPCG16B25/00G16B30/00G16B50/00G06F21/602
Inventor 张翼飞王海华赵椰肖祖颖张东裔刘翟
Owner HUNAN UNIV OF SCI & TECH
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