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Traditional Chinese medicine for treating skin wound surface

A technology of skin wounds and traditional Chinese medicine, which is applied in the direction of skin diseases, antipyretics, antibacterial drugs, etc., can solve the problems of patients' pain and discomfort, patient pain, and body fluid imbalance, so as to promote blood circulation of the epidermis, avoid the generation of scars, and inhibit Effect of infection

Inactive Publication Date: 2021-09-28
夏明好
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The medicines for the treatment of skin wounds in the prior art do not have a good inhibitory effect on the exudation of wound tissue fluid, and a large amount of exudation of tissue fluid in patients with burns and scalds (especially patients with large area burns and scalds) leads to the loss of electrolytes in patients, and the imbalance of body fluids, aggravating Increased chances of systemic infection and shock
In addition, the existing patent medicines for treating burns and scalds are mostly in ointment and powder dosage forms, and these dosage forms all need debridement treatment when changing the dressing (when the second medication is used, the debridement process cannot completely remove the drug oil film applied last time, and the The reapplied drug absorbs to form a certain barrier), the pain and discomfort of the patient in the repeated debridement process, the inflammatory exudation of the scalded patient combined with the powder drug and scab is difficult to remove, the patient will be very painful when debridement and dressing change, and even because of wound surface

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Mugwort leaf extract is made through the following steps:

[0033] Crush the dried old mugwort leaves through a 50-mesh sieve, add 8 times the mixed solution of ethanol and deionized water, heat to 96°C and reflux in a water bath for 1.5 hours, repeat twice, combine the extracts, filter, and concentrate to dryness by rotary evaporation to obtain mugwort leaves Extract, control the volume ratio of ethanol and deionized water to be 3:1.

Embodiment 2

[0035] Sophora flavescens extract is made through the following steps:

[0036] Grind the dried Sophora flavescens through a 100-mesh sieve, add a mixed solvent of acetone and ethanol 9 times the mass, soak for 10 hours, heat to 98°C and reflux for 2 hours, filter, collect the filtrate, use an ultrafiltration device, the cut-off molecular weight is 5000- 10000 of the filtrate, and then rotary evaporated to remove the solvent to obtain the Sophora flavescens extract, and the volume ratio of acetone and ethanol was controlled to be 2:1.

Embodiment 3

[0038] A kind of Chinese medicine for treating skin wounds, comprising the following raw materials in parts by weight: 3 parts of Chinese medicine composition, 70 parts of dehydrated ethanol, wherein, said Chinese medicine composition is Herba bacifera extract, Burnet burnet extract, Artemisia argyi leaves prepared in Example 1 extract, Cortex paeonol extract, Fructus Cnidii extract, Atractylodes atractylodes extract, Scutellaria baicalensis extract, Gardenia jasmine extract, Sophora flavescens extract prepared in Example 2, Peppermint extract according to mass ratio 9:7:3:3: 3:3:3:3:3:3 mixed.

[0039] The traditional Chinese medicine for treating skin wounds is made through the following steps:

[0040] After mixing the traditional Chinese medicine composition and absolute ethanol, transfer it to a homogenizer, and stir for 60 minutes at 5 MPa and 900 r / min to obtain a traditional Chinese medicine for treating skin wounds.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine for treating a skin wound surface, and belongs to the technical field of traditional Chinese medicine pharmacy. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 3 to 11 parts of traditional Chinese medicine composition and 70 to 80 parts of absolute ethyl alcohol, wherein the traditional Chinese medicine composition is prepared from radix stemonae extract, radix sanguisorbae extract, folium artemisiae argyi extract, cortex moutan extract, fructus cnidii extract, rhizoma atractylodis extract, radix scutellariae extract, fructus gardeniae extract, radix sophorae flavescentis extract and herba menthae extract. Firstly, in the wound surface hemostasis, detumescence and anti-inflammatory processes, the detumescence, hemostasis and anti-inflammatory effects of the extracts are synergistically achieved; the effects of fast easing pain and sealing the wound surface are achieved; secondly, in the whole wound surface incrustation and healing process, the antibacterial effect of the extracts is synergistically achieved; the wound surface infection is inhibited; thirdly, in the whole wound surface incrustation and healing process, the effects of promoting the epidermis blood circulation, resisting the oxidization and whitening the skin of the extracts are achieved; and the incrustation falling is promoted; the scar generation is avoided.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine pharmacy, and in particular relates to a traditional Chinese medicine for treating skin wounds. Background technique [0002] The repair and healing of various wounds on human skin is a complex pathophysiological process. Slightly injured wounds experience post-injury bleeding or exudation, dry scabs, and subscar healing. Most of the wounds with relatively large or special skin lesions (such as burns) will experience exudation, infection, necrotic tissue removal, infection control, wound exudation reduction, scabs or wounds covered by biological materials, and wounds gradually scar after injury heal. [0003] The medicines for the treatment of skin wounds in the prior art do not have a good inhibitory effect on the exudation of wound tissue fluid, and a large amount of exudation of tissue fluid in patients with burns and scalds (especially patients with large area burns and s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/904A61K9/12A61K47/10A61P17/02A61P17/04A61P29/00A61P31/04
CPCA61K36/904A61K36/739A61K36/282A61K36/71A61K36/65A61K36/234A61K36/284A61K36/539A61K36/744A61K36/489A61K36/534A61K47/10A61K9/12A61K9/0014A61P17/02A61P31/04A61P29/00A61P17/04A61K2300/00
Inventor 夏明好
Owner 夏明好
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