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Vitamin B complex tablet based on oral cavity micro-bubble rapid disintegrating formula and preparation method of vitamin B complex tablet

A multivitamin and vitamin technology, which is applied in the directions of vitamin-containing food ingredients, food forming, polysaccharide/gum-containing food ingredients, etc., can solve the problems of complex process and low production efficiency.

Inactive Publication Date: 2021-05-18
JIANGSU ALAND NOURISHMENT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Wet granulation and tabletting method is a method of compressing materials after wet granulation and drying. This method is not suitable for granulation of heat-sensitive and moisture-sensitive materials; dry granulation and tabletting is a method of compressing materials after dry granulation. The tablet method is often used in the tablet production of water-unstable materials, and both of the above two methods need to go through the granulation process before they can be pressed into tablets. The process is more complicated and the production efficiency is lower.

Method used

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  • Vitamin B complex tablet based on oral cavity micro-bubble rapid disintegrating formula and preparation method of vitamin B complex tablet
  • Vitamin B complex tablet based on oral cavity micro-bubble rapid disintegrating formula and preparation method of vitamin B complex tablet
  • Vitamin B complex tablet based on oral cavity micro-bubble rapid disintegrating formula and preparation method of vitamin B complex tablet

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A multivitamin B tablet based on oral microfoam rapid disintegration formula, including 0.2% folic acid, 0.33% biotin, 0.22% vitamin B2, 0.27% vitamin B6, 1.52% niacinamide, 0.04% vitamin B12 , 0.28% thiamine nitrate, 0.64% calcium pantothenate, 22.18% mannitol starch polymer, 22.18% sorbitol, 22.18% isomalt, 12% citric acid, 15% bicarbonate Sodium, 0.5% Magnesium Stearate, 0.2% Aspartame, 0.07% Sucralose, 0.7% Steviol Glycosides, 1.5% Grapefruit Flavored Powder Flavor with Mannitol Starch Polymerized The material ratio of citric acid, sorbitol and isomaltulose is 1:1:1, and the material ratio of citric acid and sodium bicarbonate is 4:5. The dosage formula is as follows:

[0023]

Embodiment 2

[0025] A multivitamin B tablet based on oral microfoam rapid disintegration formula, including 0.2% folic acid, 0.33% biotin, 0.22% vitamin B2, 0.27% vitamin B6, 1.52% niacinamide, 0.04% vitamin B12 , 0.28% thiamine nitrate, 0.64% calcium pantothenate, 33.26% mannitol starch polymer, 16.63% sorbitol, 16.63% isomalt, 15% citric acid, 12% bicarbonate Sodium, 0.5% Magnesium Stearate, 0.2% Aspartame, 0.07% Sucralose, 0.7% Steviol Glycosides, 1.5% Grapefruit Flavored Powder Flavor with Mannitol Starch Polymerized substance, sorbitol, isomaltulose, the material ratio of the three is 2:1:1, citric acid and sodium bicarbonate, the material ratio of the two is 5:4, and the described lubricant selects stearin Magnesium acid, calcium pantothenate is selected as the absorption-promoting material. The dosage formula is as follows:

[0026]

[0027]

Embodiment 3

[0029] A multivitamin B tablet based on oral microfoam rapid disintegration formula, including 0.2% folic acid, 0.33% biotin, 0.22% vitamin B2, 0.27% vitamin B6, 1.52% niacinamide, 0.04% vitamin B12 , 0.28% thiamine nitrate, 22.18% mannitol starch polymer, 22.18% sorbitol, 22.18% isomalt, 15% citric acid, 12% sodium bicarbonate, 0.5% hard Magnesium steatate, 0.64% calcium pantothenate, 0.2% aspartame, 0.07% sucralose, 0.7% steviol glycosides, 1.5% grapefruit flavored powder flavor with mannitol starch polymerized Material, sorbitol, isomaltulose, the material ratio of the three is 1:1:1, and the material ratio of citric acid and sodium bicarbonate is 5:4. The dosage formula is as follows:

[0030]

[0031]

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PUM

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Abstract

The invention discloses a vitamin B complex tablet based on an oral cavity micro-bubble rapid disintegration formula. The tablet comprises the following raw materials in percentage by mass: 0.15%-0.2% of folic acid, 0.25%-0.4% of biotin, 0.2%-0.3% of vitamin B2, 0.2%-0.3% of vitamin B6, 1.5%-2.0% of nicotinamide, 0.01%-0.04% of vitamin B12, 0.2%-0.35% of thiamine nitrate, 0.5%-0.7% of calcium pantothenate, 20%-35% of a mannitol starch compound, 15%-25% of sorbitol, 15%-25% of isomaltitol, 15%-17% of anhydrous citric acid, 10%-14% of sodium bicarbonate, 0.2%-0.3% of aspartame, 0.05%-0.1% of sucralose, 0.5%-1% of stevioside, 1%-2% of edible essence and 0.45%-0.55% of magnesium stearate. The vitamin B complex tablet can be rapidly disintegrated in the oral cavity, the experience feeling of the tablet is good, and a preparation method has the characteristics of simple process and high production efficiency.

Description

technical field [0001] The invention relates to the technical field of health food, in particular to a compound vitamin B tablet based on an oral microbubble rapid disintegration formula and a preparation method thereof. Background technique [0002] Health food supplement tablets generally include effervescent tablets, swallowable tablets, buccal tablets, and chewable tablets. [0003] Due to the composition of the formula, the effervescent tablet is an acidic drink after melting, which has an irritating effect on the teeth. If it is taken for a long time or taken on an empty stomach for a long time, it will cause a load on the gastrointestinal tract, causing acid reflux, heartburn, and hyperacidity Side effects of reflux and hypersecretion of gastric acid; at the same time, effervescent tablets contain more sodium, and taking large amounts for a long time will increase the risk of cardiovascular and cerebrovascular diseases. People with high blood lipids and blood pressur...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/15A23L33/10A23L29/30A23L27/30A23P10/28
CPCA23L33/15A23L33/10A23L29/30A23L29/37A23L29/015A23L29/035A23L27/32A23L27/37A23L27/36A23L29/04A23P10/28A23V2002/00A23V2250/7056A23V2250/72A23V2250/7044A23V2250/7052A23V2250/706A23V2250/7042A23V2250/642A23V2250/6412A23V2250/51A23V2250/2482A23V2250/264A23V2250/262A23V2250/1576A23V2250/1614A23V2250/032
Inventor 贺庆陈权随建强黄小平张国栋徐红芬
Owner JIANGSU ALAND NOURISHMENT
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