Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Three Chinese magnoliavine fruit extracts as well as preparation process and application thereof

A Schisandra chinensis extract and a preparation process technology, which are applied in the field of medicine, can solve the problem that alcohol methylation cannot be fully raised, and achieve the effects of large reduction, small dosage, and reduced side effects.

Active Publication Date: 2021-05-14
沈嘉
View PDF2 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The main active components of Schisandra chinensis, total lignans, are all fat-soluble components. If the total lignans are to be extracted efficiently, the CSFE conditions selected are usually able to highly enrich non-polar components such as schisandra B, which is relatively lipophilic. process conditions, and such process conditions cannot fully propose the relatively large polar alcohol form in the total lignans of Schisandra chinensis
Thereby, still lack at present the method for more fully extracting the total lignans and other active ingredients in Schisandra fruit

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Three Chinese magnoliavine fruit extracts as well as preparation process and application thereof
  • Three Chinese magnoliavine fruit extracts as well as preparation process and application thereof
  • Three Chinese magnoliavine fruit extracts as well as preparation process and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0030] The present invention is described in detail below in conjunction with accompanying drawing.

[0031] The invention provides three kinds of schisandra extracts and their preparation process, and the preparation process of the three kinds of schisandra extracts is a reference Figure 1-2 , the specific process is as follows:

[0032]Firstly apply the carbon dioxide supercritical extraction process, take a certain amount of dry Schisandra fruit, crush it properly, add ethanol solution (concentration 70-90vol.%) accounting for 3-15% of Schisandra raw material weight as a carrier agent, extraction pressure 30MPa, extraction temperature 40°C, CO 2 The flow rate is 2L / min, and the oil emulsion of Schisandra chinensis is obtained, which is the fat-soluble extract A. (Carbon dioxide can be recycled.)

[0033] The prepared fat-soluble extract A was placed at room temperature, and separated into layers after standing: the upper layer was oily oil, which was extract B. The low...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses three Chinese magnoliavine fruit extracts as well as a preparation process and application thereof, and belongs to the technical field of medicines. The preparation method of the Chinese magnoliavine fruit extract comprises the following steps: treating Chinese magnoliavine fruit by using a CSFE method to obtain an extract A, and placing the extract at room temperature for layering to obtain an extract B (rich in schisandrin B) and an extract C (rich in schizandrin); boiling the decoction dregs, adding beta-cyclodextrin into filtrate to carry out inclusion adsorption on residual fat-soluble active ingredients in the decoction dregs, and filtering to obtain the inclusion adsorption lignan; performing concentration and alcohol precipitation on the filtrate to obtain the Chinese magnoliavine fruit polysaccharide; respectively combining the inclusion adsorption lignan and polysaccharide with the extracts A, B and C to obtain an extract I, an extract II and an extract III. The content of effective parts of the three extracts accounts for more than 50% of the extracts, the three extracts are composed of three active components including total lignan, linoleic acid and polysaccharide, and the total lignan is 18-25%. Different new drugs can be developed from the three extracts according to different proportions of schisandrin B and schizandrin for resisting depression, promoting sleep, promoting intelligence and other indications.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to three kinds of schisandra extracts and their preparation process and application. Background technique [0002] Schisandra chinensis (Northern Schisandra) is mainly distributed in northeast my country and northern Inner Mongolia. The fruit is used as medicine. It is mainly used for anti-depression, sleep, sedation, intelligence development, liver protection, and hypoglycemic effect. The main pharmacodynamic active ingredient of Schisandra chinensis is the total lignans of Schisandra chinensis, and the lignans with the highest content are schisandrin A and schisandrin B. Studies have shown that the content of alcohol A in the dried and mature fruit of Schisandra chinensis is much higher than that of alcohol B. The quality standard of Schisandra chinensis recorded in the Chinese Pharmacopoeia in 2015, the content is determined by high performance liquid chromatography, and the dr...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/79A61K36/57A61P25/24A61P25/20A61P25/28A61K131/00
CPCA61K36/79A61K36/57A61P25/24A61P25/20A61P25/28A61K2236/37A61K2236/333A61K2236/331A61K2236/55Y02P20/54
Inventor 沈嘉
Owner 沈嘉
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com