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Disinfectant for quickly inactivating coronaviruses

A coronavirus and disinfectant technology, which is applied in the field of disinfectant for rapid inactivation of coronavirus, can solve problems such as inability to apply wounds, mucous membranes, narrow application range, corrosion, etc., to achieve convenient transportation and use, rapid mass production, The effect of simple process operation

Pending Publication Date: 2021-04-09
上海海禾医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the traditional disinfectants in the domestic market are mostly bactericidal. They have weak inactivation ability for coronaviruses and need to act for more than a few minutes. Disinfectants that can inactivate viruses with a shorter action time, such as chlorine-containing disinfectants, are generally used. Disinfection on the surface of objects and the environment, while alcohol-based disinfectants can only be applied to hands and skin, and cannot be applied to wounds, mucous membranes, etc.
In addition, traditional disinfectants also have disadvantages such as narrow application range, flammability, explosion, corrosion, and large irritation.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] A kind of disinfectant solution for rapid inactivation of coronavirus, by mass percentage, consists of the following components:

[0020] Compound quaternary ammonium salt 0.1%,

[0021] Alkylphenol ethoxylates 1%,

[0022] Triethanolamine 0.1%,

[0023] The balance is water.

[0024] Wherein, the compound quaternary ammonium salt is didecyldimethylammonium chloride, dioctyldimethylammonium chloride, dodecyldimethylbenzylammonium chloride, hexadecyldimethylbenzylammonium Ammonium chloride mixture, double decyl dimethyl ammonium chloride, dioctyl dimethyl ammonium chloride, dodecyl dimethyl benzyl ammonium chloride, hexadecyl dimethyl ammonium chloride in complex quaternary ammonium salts The ratio of benzyl ammonium chloride is 2:2:6:1.

Embodiment 2

[0026] A kind of disinfectant solution for rapid inactivation of coronavirus, by mass percentage, consists of the following components:

[0027] Compound quaternary ammonium salt 0.15%,

[0028] Fatty alcohol polyoxyethylene ether 2%,

[0029] Potassium hydroxide 0.8%,

[0030] The balance is water.

[0031] Wherein, the compound quaternary ammonium salt is didecyldimethylammonium chloride, dioctyldimethylammonium chloride, dodecyldimethylbenzylammonium chloride, hexadecyldimethylbenzylammonium Ammonium chloride mixture, double decyl dimethyl ammonium chloride, dioctyl dimethyl ammonium chloride, dodecyl dimethyl benzyl ammonium chloride, hexadecyl dimethyl ammonium chloride in complex quaternary ammonium salts The ratio of benzyl ammonium chloride is 3:3:2:1.

Embodiment 3

[0033] A kind of disinfectant solution for rapid inactivation of coronavirus, by mass percentage, consists of the following components:

[0034] Compound quaternary ammonium salt 0.2%,

[0035] Fatty alcohol polyoxyethylene ether 5%,

[0036] Sodium hydroxide 0.5%,

[0037] The balance is water.

[0038] Wherein, the compound quaternary ammonium salt is didecyldimethylammonium chloride, dioctyldimethylammonium chloride, dodecyldimethylbenzylammonium chloride, hexadecyldimethylbenzylammonium Ammonium chloride mixture, double decyl dimethyl ammonium chloride, dioctyl dimethyl ammonium chloride, dodecyl dimethyl benzyl ammonium chloride, hexadecyl dimethyl ammonium chloride in complex quaternary ammonium salts The ratio of benzyl ammonium chloride is 2:3:4:1.

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PUM

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Abstract

The invention discloses disinfectant for quickly inactivating coronaviruses. The disinfectant consists of the following ingredients in parts by weight: 0.1-0.2% of compound quaternary ammonium salt, 1-5% of nonionic surfactant, 0-1% of pH regulating agent and the balance of water, wherein the compound quaternary ammonium salt is a mixture of didecyl dimethyl ammonium chloride, dioctyl dimethyl ammonium chloride, dodecyl dimethyl benzyl ammonium chloride and cetylhexadecyl dimethyl benzyl ammonium chloride. The disinfectant for quickly inactivating the coronaviruses adopts the compound quaternary ammonium salt, and therefore, the disinfectant has a high inactivation capacity for the human coronavirus 229E. If the stock solution of the disinfectant acts for one minute, an inactivation logarithm value for the human coronavirus 229E is greater than 4.00, i.e., an inactivation rate is 99.99%. The disinfectant is non-irritating, can be applied to quick disinfection of each position of the human body, including the hands, the skin, the wound surface, the mucous membrane and the like, is unlikely to burn or explode, and can be conveniently transported and used.

Description

technical field [0001] The invention relates to the technical field of disinfection products, in particular to a disinfectant for rapidly inactivating coronaviruses. Background technique [0002] Quaternary ammonium salt disinfectants are non-flammable and non-explosive, and are less irritating to the human body. Since they were put into production in the 1950s, there have been hundreds of varieties, only a few of which have good bactericidal effects, including single-chain quaternary ammonium salts and Double chain quaternary ammonium salt disinfectant. At present, the traditional disinfectants in the domestic market are mostly bactericidal. They have weak inactivation ability for coronaviruses and need to act for more than a few minutes. Disinfectants that can inactivate viruses with a shorter action time, such as chlorine-containing disinfectants, are generally used. Disinfection on the surface of objects and the environment, and alcohol-based disinfectants can only be a...

Claims

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Application Information

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IPC IPC(8): A61K31/14A61P31/14
CPCA61K31/14A61K9/0014A61K47/18A61K47/10A61P31/14A61K2300/00
Inventor 刘志刚王珏
Owner 上海海禾医疗科技有限公司
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