Sucralose continuous high-temperature reaction method and device thereof

Abstract

The invention relates to a sucralose continuous high-temperature reaction method and a device thereof, which are characterized in that (1) low-temperature chlorination liquid is heated by a 1 # reboiler and then is fed into a 1 # high-temperature chlorination reaction tower, the temperature in the tower is controlled to be 68-71 DEG C, the pressure is -4-2Mpa, gas from the tower top returns to thetower after being condensed, and is circularly heated for 30min to obtain a solution A; (2) the solution A is heated by a 2 # reboiler and then enters a 2 # high-temperature chlorination reaction tower, the temperature in the tower is controlled to be 98-101 DEG C, the pressure in the tower is controlled to be -4-2 Mpa, gas coming out of the tower top is condensed and then returns to the tower, cyclic heating is conducted for 60 min, and a solution B is obtained; and (3) the solution B is heated by a 3 # reboiler and then enters a 3 # high-temperature chlorination reaction tower, the temperature in the tower is controlled to be 109-111 DEG C, the pressure in the tower is controlled to be -4-2 Mpa, gas coming out of the tower top is condensed and then returns to the tower, cyclic heating is conducted for 120 min, and a solution C is obtained. The device has the advantages that the three high-temperature chlorination reaction towers are connected in series, so that continuous reaction can be realized, the heating rate is increased, the pressure and the heating environment of a high-temperature chlorination system are optimized, the quality and the yield of a product are improved, and the tail gas emission amount is reduced.

Description

technical field [0001] The invention belongs to the technical field of sucralose production, and relates to a method and device for continuous high-temperature reaction of trichloroethane. Background technique [0002] Sucralose is obtained by replacing the hydroxyl groups at positions 4, 1, and 6 in the sucrose molecule with chlorine atoms. There are a total of 8 hydroxyl groups in the sucrose molecule. It is of course very difficult to replace 3 hydroxyl groups at specific positions by selective chlorination without changing the hydroxyl groups at other positions, and because the hydroxyl groups at each position The reactivity of sucralose varies, making the synthesis of sucralose more difficult. Most of the existing processes are to put the esterified liquid that has been reacted at low temperature into a high-temperature reactor for three-stage high-temperature reaction. Most of them are single-pot reactions, the reaction is discontinuous, the reaction is not easy to co...

AI Technical Summary

Problems solved by technology

There are a total of 8 hydroxyl groups in the sucrose molecule. It is of course very difficult to replace 3 hydroxyl groups at specific positions by selective chlorination without changing the hydroxyl groups at other positions, and because the hydroxyl groups at each position The reactivity of sucralose varies, making the synthesis of sucralose more difficult

Most of the existing processes are to put the esterified liquid that has been reacted at low temperature into a high-temperature reactor for three-stage high-temperature reaction, mostly a single-pot reaction, the reaction is discontinuous, the reaction is not easy to control, the reaction is insufficient, time-consuming and labor-intensive, resulting in increase in production costs

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