Marine oligosaccharide-containing composition for preventing and treating gout

Abstract

The invention discloses a marine oligosaccharide-containing composition for preventing and treating gout. The marine oligosaccharide-containing composition is prepared from marine oligosaccharide as amain active ingredient. The marine oligosaccharide is a small molecular sugar chain obtained by degrading marine animal polysaccharide, algal polysaccharide and microbial polysaccharide with chemicaland biological enzyme methods, and mainly comprises chitosan oligosaccharide, mannuronic acid oligosaccharide, guluronic acid oligosaccharide, agar oligosaccharide, neoagaro-oligosaccharide, carrageenan oligosaccharide and the like. Test results show that the marine oligosaccharide can certainly inhibit the effect of mouse liver xanthine oxidase XOD, reduce in-vivo generation of uric acid, reducedeposition of urate substances in the kidney, accelerate uric acid metabolism and relieve gouty arthritis induced by sodium urate. Besides, the marine oligosaccharide can also reduce inflammatory response, improve body immunity and play a certain role in easing pain, is used for preparing drugs or health care products for preventing and treating gout, and can provide a natural or nature-imitateddrug for preventing and treating gout, so that adverse reactions caused by using the gout drugs are reduced.

Description

technical field [0001] The invention discloses a composition containing marine oligosaccharides for preventing and treating gout, and specifically belongs to the technical field of marine biology. Background technique [0002] Gout is a disease in which urate is deposited in tissues due to metabolic disorders, increased blood uric acid levels and / or decreased excretion of uric acid. Clinically, gout is mainly characterized by hyperuricemia, manifested as recurrent arthritis, tophi formation and joint deformity, severe cases can cause joint mobility disorders, and chronic interstitial nephritis and uric acid nephritis can be caused when the kidney is involved. stone disease. Hyperuricemia is the biochemical basis of gout, and gout must be accompanied by hyperuricemia. In recent years, the incidence of gout and hyperuricemia is on the rise, and the age of onset is getting younger. They are closely related to the occurrence of hypertension, hyperlipidemia, atherosclerosis, an...

AI Technical Summary

Problems solved by technology

These drugs achieve the purpose of relieving or treating gout and hyperuricemia through different action links, but more and more clinical observations have found that they all have certain toxic and side effects

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