A high-efficiency inactivation device for vaccines

Abstract

A high-efficiency inactivation device for vaccines, comprising a tank body, a feed inlet, a temperature sensing device, a stirring device, a discharge port and an electric discharge device, the top of the tank body is provided with a feed inlet and a temperature sensing device, A stirring device is arranged below the temperature sensing device, and the stirring device is arranged inside the tank body, the timing switch is arranged inside the tank body, an ultrasonic generator is arranged at the bottom of the tank body, and the The tank wall of the tank body is provided with a discharge port, the discharge port is connected with the electric discharge device, and the electric discharge device is arranged on one side of the tank body; in terms of temperature control, the present invention adopts electric heating The layer is directly heated, the temperature is accurate and clear, and it is easy to control. The internal temperature sensing probe is used to directly monitor the temperature required for inactivation, reduce the deviation, and greatly improve the success rate of inactivation; the invention adds an ultrasonic generator, an ultrasonic generator Further achieve the effect of inactivation.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical production, in particular to a high-efficiency inactivation device for vaccines. Background technique [0002] Inactivated vaccines refer to culturing viruses or bacteria first, and then inactivating them with heating, chemical reagents and ultrasonic waves. Inactivated vaccines can be composed of whole viruses or bacteria. [0003] Most of the traditional vaccine inactivation methods use physical inactivation. Traditional physical inactivation uses a single method of heating to kill viruses or a single method of ultrasonic cracking cells. The inactivation effect is not ideal and the inactivation efficiency is not high; The success rate is low, and it is difficult to guarantee the purity of vaccines that are often needed; the jacket of the vaccine inactivation tank provides the required temperature by controlling the water temperature, and the temperature control often has deviations, and t...

AI Technical Summary

Problems solved by technology

[0003] Most of the traditional vaccine inactivation methods use physical inactivation. Traditional physical inactivation uses a single method of heating to kill viruses or a single method of ultrasonic cracking cells. The inactivation effect is not ideal and the inactivation efficiency is not high; The success rate is low, and it is difficult to guarantee the purity of vaccines that are often needed; the jacket of the vaccine inactivation tank provides the required temperature by controlling the water temperature. The preparation work is long, which affects the overall inactivation efficiency; most of the existing inactivation devices are non-airtight devices, which will cause the original inactivated vaccine to be polluted in a non-airtight environment, which will affect the inactivation efficiency; The automation level of the living device is not high, and most of them are manually operated. Manual contact will pollute the inactivated vaccine, and the inactivation efficiency is low

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