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Liquid trehalose dressing for skin barrier wound repair and preparation method thereof

A technology for wound repair and skin barrier, applied in medical science, climate change adaptation, bandages, etc., can solve problems such as antibacterial and anti-infection, insufficient wound healing effect, lack of skin wound care function, and affect skin barrier function, etc., to achieve enhanced Soothing and nursing functions, accelerating wound healing, and shortening wound healing time

Active Publication Date: 2020-11-20
海南鸿翼医疗器械有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] With the development of society, people's pursuit of beauty is getting higher and higher. At present, the research on laser, fruit acid skin peeling, microdermabrasion, water light and microneedling is being deepened and widely used. At the same time, certain After wound surgery, the skin epidermis will often be damaged to varying degrees, affecting the skin barrier function, and prone to skin symptoms such as skin erythema, edema, and pigmentation. Therefore, how to effectively treat laser, fruit acid skin peeling, micro Wound repair after crystal grinding, hydrolight and microneedling has become an important research hotspot
[0003] Existing medical dressing products for wound repair are few. Although the current trehalose dressing can play a certain auxiliary repairing effect on the skin, it can reduce the evaporation of water on the skin surface and play a role in moisturizing and moisturizing the skin. However, the existing seaweed Sugar dressings are not effective in antibacterial, anti-infection, wound healing, etc., and lack of care for skin wounds, which makes the wound repair cycle longer and prone to secondary infection of the wound.

Method used

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  • Liquid trehalose dressing for skin barrier wound repair and preparation method thereof
  • Liquid trehalose dressing for skin barrier wound repair and preparation method thereof
  • Liquid trehalose dressing for skin barrier wound repair and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Embodiment 1 - a liquid trehalose dressing for skin barrier wound repair, including the following raw materials according to the ratio of parts by weight: 8 parts of trehalose, 1 part of complex polysaccharide, 0.5 part of ε-polylysine, 0.5 part of bamboo leaf flavonoids Ethanol extract, 0.03 parts of lactobacillus / soybean milk fermentation product filtrate, 12 parts of sodium hyaluronate, 5 parts of collagen, 1.5 parts of polyol humectant and 1000 parts of water;

[0025] The complex polysaccharide is mixed with black soybean crude polysaccharide, spirulina polysaccharide, tremella heteropolysaccharide and konjac glucomannan with a mass ratio of 5:3:3:1; the polyol moisturizing agent is composed of a mass ratio of A 1:5:8 blend of sorbitol, glycerin and propylene glycol.

Embodiment 2

[0026] Embodiment 2 - a liquid trehalose dressing for skin barrier wound repair, including the following raw materials according to the ratio of parts by weight: 10 parts of trehalose, 3 parts of complex polysaccharides, 0.8 parts of ε-polylysine, 1.5 parts of bamboo leaf flavonoids Ethanol extract, 0.06 part of lactobacillus / soybean milk fermentation product filtrate, 15 parts of sodium hyaluronate, 6 parts of collagen, 2.5 parts of polyol humectant, 0.02 part of preservative and 1100 parts of water;

[0027] The complex polysaccharide is mixed with black soybean crude polysaccharide, spirulina polysaccharide, tremella heteropolysaccharide and konjac glucomannan with a mass ratio of 8:3:3:1; the polyol moisturizing agent is composed of a mass ratio of 1:5:8 of sorbitol, glycerol and propylene glycol mixed; the preservative is phenoxyethanol.

Embodiment 3

[0028] Embodiment 3 - a liquid trehalose dressing for skin barrier wound repair, including the following raw materials according to the ratio of parts by weight: 9 parts of trehalose, 2 parts of complex polysaccharides, 0.7 parts of ε-polylysine, 0.8 parts of bamboo leaf flavonoids Ethanol extract, 0.04 part of lactobacillus / soybean milk fermentation product filtrate, 14 parts of sodium hyaluronate, 5.5 parts of collagen, 2.3 parts of polyol humectant, 0.01 part of preservative and 1100 parts of water;

[0029] The complex polysaccharide is mixed with black soybean crude polysaccharide, spirulina polysaccharide, tremella heteropolysaccharide and konjac glucomannan with a mass ratio of 7:3:3:1; the polyol moisturizing agent is composed of a mass ratio of 1:5:8 of sorbitol, glycerol and propylene glycol mixed; the preservatives are paraben esters.

[0030] The preparation method of the liquid trehalose dressing for skin barrier wound repair of embodiments 1-3 comprises the follo...

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Abstract

The invention provides a liquid trehalose dressing for skin barrier wound repair and a preparation method thereof. The liquid trehalose dressing comprisese 8 to 10 parts of trehalose, 1 to 5 parts ofcompound polysaccharide, 1 to 3 parts of epsilon-polylysine, 0.5 to 1.5 parts of an ethanol extract of bamboo leaf flavonoid, 0.03 to 0.06 part of a lactic acid bacillus / soybean milk fermentation product filtrate, 12 to 15 parts of sodium hyaluronate, 5 to 6 parts of collagen, 1.5 to 2.5 parts of a polyol humectant and 1000 to 1100 parts of water. According to the invention, a more stable and moist microenvironment with good air permeability is provided for wound healing; good antibacterial, anti-inflammatory and anti-oxidation effects and a wound surface nursing function are achieved; pigmentation is reduced; stimulation effect on the skin of a wound surface is reduced; the ability of the skin in adapting to the environment is improved; wound surface healing time is shortened; and the dressing can be widely applied to auxiliary repair of wound surfaces produced in laser and tartaric acid skin replacement, microcrystal grinding, hydro lifting and microacupunoture.

Description

technical field [0001] The invention relates to the technical field of medical dressings, in particular to a liquid trehalose dressing for skin barrier wound repair and a preparation method thereof. Background technique [0002] With the development of society, people's pursuit of beauty is getting higher and higher. At present, the research on laser, fruit acid skin peeling, microdermabrasion, water light and microneedling is being deepened and widely used. At the same time, certain After wound surgery, the skin epidermis will often be damaged to varying degrees, affecting the skin barrier function, and prone to skin symptoms such as skin erythema, edema, and pigmentation. Therefore, how to effectively treat laser, fruit acid skin peeling, micro Wound repair after crystal grinding, hydrolight and microneedling has become an important research hotspot. [0003] Existing medical dressing products for wound repair are few. Although the current trehalose dressing can play a ce...

Claims

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Application Information

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IPC IPC(8): A61L26/00
CPCA61L26/0066A61L26/0057A61L26/0019A61L26/0023A61L26/0033A61L2300/216A61L2300/41A61L2300/404A61L2300/412Y02A40/90
Inventor 陈震王虹韵
Owner 海南鸿翼医疗器械有限公司
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